Patents Assigned to Spojene Podniky Prozdravotnickou Vyrobu (SPOFA)
  • Etheric derivative of 4(3H)-quinazolinone and a process for preparation thereof
    Patent number: 4973691
    Abstract: An etheric derivative of 4(3H)-quinazolinone which is a fluorinated 3-[2-(4-biphenylyloxy)ethyl]-4(3H)-quinazolinone, produced by reacting said 4(3H)-quinazolinone with the corresponding fluorinated 4-(2-chloroethoxy)biphenyl, and its acid addition salts, especially the hydrochloride. This compound possesses substantially higher analgesic activity and lower acute toxicity than aminophenazone, ibuprofen, acetylosalicyclic acid and paracetamol.
    Type: Grant
    Filed: November 1, 1989
    Date of Patent: November 27, 1990
    Assignee: Spojene Podniky Prozdravotnickou Vyrobu (SPOFA)
    Inventors: Ludmila Fisnerova, Bohumila Brunova, Eva Maturova, Jaroslava Grimova