Abstract: Methods for treating cognitive/attention deficit disorders in general using tetrahydroindolone derivatives and analogues, particularly tetrahydroindolone derivatives or analogues in which the tetrahydroindolone derivative or analogue is covalently linked to another moiety to form a bifunctional conjugate are disclosed. More specifically, methods and compositions for treating attention deficit disorder and attention deficit hyperactivity disorders in adults and children as well as mild cognitive impairment and dementia are provided.
Type:
Grant
Filed:
December 1, 2004
Date of Patent:
May 12, 2009
Assignee:
Sprectrum Pharmaceuticals, Inc.
Inventors:
Alvin Jerald Glasky, David B. Fick, David R. Helton