Abstract: Disclosed herein are compositions and methods for increasing lifespan, for preventing or treating a disease including an aging-related disorder, for reducing a symptom of aging, and/or boosting an immune system in a mammal. Also disclosed herein are compositions and methods for improving effectiveness of a vaccine in a mammal. The compositions comprise, at least, a therapeutically effective amount of disulfiram and one or more additional ingredients.
Type:
Grant
Filed:
June 7, 2021
Date of Patent:
March 28, 2023
Assignee:
Spring Discovery, Inc.
Inventors:
Rachel Jacobson, Wendy Cousin, An Nguyen, Tempest Plott, William Van Trump, Dat Nguyen, Daniel Chen, Jarred Heinrich, Ben Komalo, Lauren Nicolaisen, Christian Elabd
Abstract: Disclosed herein are compositions and methods for increasing lifespan, for preventing or treating a disease including an aging-related disorder, for reducing a symptom of aging, and/or boosting an immune system in a mammal. Also disclosed herein are compositions and methods for improving effectiveness of a vaccine in a mammal. The compositions comprise, at least, a therapeutically effective amount of disulfiram and one or more additional ingredients.
Type:
Grant
Filed:
January 14, 2021
Date of Patent:
July 20, 2021
Assignee:
Spring Discovery, Inc.
Inventors:
Rachel Jacobson, Wendy Cousin, An Nguyen, Tempest Plott, William Van Trump, Dat Nguyen, Daniel Chen, Jarred Heinrich, Ben Komalo, Lauren Nicolaisen, Christian Elabd
Abstract: Disclosed herein are compositions and methods for increasing lifespan, for preventing or treating a disease including an aging-related disorder, for reducing a symptom of aging, and/or boosting an immune system in a mammal. Also disclosed herein are compositions and methods for improving effectiveness of a vaccine in a mammal. The compositions comprise, at least, a therapeutically effective amount of disulfiram and one or more additional ingredients.
Type:
Grant
Filed:
January 14, 2021
Date of Patent:
June 15, 2021
Assignee:
Spring Discovery, Inc.
Inventors:
Rachel Jacobson, Wendy Cousin, An Nguyen, Tempest Plott, William Van Trump, Dat Nguyen, Daniel Chen, Jarred Heinrich, Ben Komalo, Lauren Nicolaisen, Christian Elabd
Abstract: The present disclosure provides systems, media, and methods for applying machine learning to determine the biological age of a sample. A method of using a biological age predictor may comprise: (a) providing data of a sample to the biological age predictor; (b) treating the sample with a substance, thereby generating a treated sample; and (c) providing data of the treated sample to the biological age predictor. The biological age predictor may generate the first biological age and/or the second biological age.
Type:
Grant
Filed:
January 23, 2019
Date of Patent:
January 5, 2021
Assignee:
Spring Discovery, Inc.
Inventors:
Ben Kamens, Ben Komalo, Wendy Cousin, Christian Elabd, Charlie Marsh, Lauren Nicolaisen