Abstract: The invention relates to radiopaque liquid embolic composition comprising tetra iodo compound, 4,4-bis (4-hydroxy-3,5 diiodo phenyl) valeric acid (IBHV) of Formula I, covalently linked to ethylene vinyl alcohol copolymer (EVOH) and dissolved in a water miscible organic liquid.

Abstract: In one aspect of the invention, the present invention discloses and claims a recombinant transforming growth factor alpha (TGF ?) consisting of Sequence ID No.: 1, craving out from the whole TGF ?, and cloned for the wound healing applications. Further it discloses primers for amplifying TGF ? consisting of Sequence ID Nos.: 2 and 3, wherein sequence ID No.: 2 is forward primer, and the sequence ID No.: 3 is reserve primer for TGF ?. It further discloses a process of preparation of a vector comprising essentially of Sequence ID No.: 1, said process comprising the steps of multiplying the desired gene fragment through PCR using primers of Sequence ID No.: 2 and 3. Further, a pharmaceutical composition comprising essentially of Sequence ID No.: 1, along with additives, fillers and addendums is disclosed. Finally, it discloses a method of wound healing using the recombinant TGF ? comprising application of a pharmaceutical composition.

Abstract: A 3D bioprintable ink formulation capable of multidimensional printing comprises gelatin modified by an essential amino acid arginine, oxidized alginate and a catalyst.

Abstract: The invention relates to radiopaque liquid embolic composition comprising tetra iodo compound, 4,4-bis (4-hydroxy-3,5 diiodo phenyl) valeric acid (IBHV) of Formula I, covalently linked to ethylene vinyl alcohol copolymer (EVOH) and dissolved in a water miscible organic liquid.

Abstract: A flow diverter device is used to redirect the blood flow inside the cerebral blood vessels and for the reduction of blood flow to the aneurysm, hence preventing the chance of aneurysm rupture as well as promoting the healing of the aneurysm. The novel design of the device, using a set of thicker wires, provides high kink resistance and radial strength. Two patterns of inter-braiding the thicker set of wires with the finer braid are disclosed, one having a checker-board and the other a ring structure. Both patterns are highly kink resistant with the checker-board design providing minimal loss in flexibility, whereas the ring design provides greater radial strength. The device could be made of super elastic materials like Nitinol wires with the thicker set being radio opaque. The device is highly kink resistant and sufficiently flexible for use in vasculature with complex bends.

Abstract: The present invention relates to a device (D) for occluding atrial septal defect. Non-woven wires are introduced in one or more stages, with each stage interspaced with one or more braids and braided together with the wires from the woven centre and earlier stages to form the device (D). The transcatheter device (D) has two discs (101, 102) one a hub-less disc incorporating a woven central section on the left atrial side and the other disc on the right atrial side with a connecting neck (110) braided from wires. The device (D) has thrombogenic material in either discs (101, 102). A ridge (108) is configured on the periphery of either the left atrial disc or right atrial disc or both discs to improve structural stability of the device and provides enhanced elapsing force onto the septum reducing chances of migration.

Abstract: This invention relates to an albumin-curcumin conjugate for application in cancer therapy, including albumin and curcumin.

Abstract: Provided herein is a drug delivery system for curcumin comprising fibrinogen, thrombin and curcumin.

Abstract: The invention relates to an anti-diabetic agent obtained from the plant Humboldtia decurrens, an anti-diabetic formulation comprising an effect amount of the extract obtained from the plant Humboldtia decurrens optionally together with additives, a process for obtaining the anti-diabetic agent, and a method for treatment of diabetes.