Abstract: A seal-break pliers used to separate components in food processing, chemical, or pharmaceutical manufacturing or processing system. The seal-break pliers including a first section and a second section. Each section includes a handle, a head section, and a transition section disposed and angularly orientated between the handle and the head section. A fastener pivotally couples the first section to the second section such that displacing the first and second handles toward each other results in a relative movement of the head sections toward each other. Each head portion includes a guide projection, a flange notch adjacent to the guide projection, and a wedge projection adjacent to the flange notch. The flange notch is configured to receive a portion of the flange of a component. The wedge projection may include a pointed edge proximate the flange notch and an inclined surface extending away from the pointed edge.