Abstract: The instant invention provides compositions and methods for determining cell interactions that are faster than conventional methods and that require the use of fewer reagents than conventional methods.
Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. Specifically, the invention herein provides a robust and reproducible method for coating sensor surfaces with aldehyde functional groups as well as methods for testing the efficiency and completeness of the coating process.
Abstract: Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical devices.
Type:
Application
Filed:
September 9, 2002
Publication date:
April 10, 2003
Applicant:
SRU Biosystems LLC
Inventors:
Bo Lin, Jane Pepper, Brian T. Cunningham, John Gerstenmaier, Peter Li, Jean Qiu, Homer Pien
Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An instrument system for detecting a biochemical interaction on a biosensor. The system includes an array of detection locations comprises a light source for generating collimated white light. A beam splitter directs the collimated white light towards a surface of a sensor corresponding to the detector locations. A detection system includes an imaging spectrometer receiving the reflected light and generating an image of the reflected light.
Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.
Type:
Application
Filed:
June 26, 2002
Publication date:
February 13, 2003
Applicant:
SRU Biosystems, LLC
Inventors:
Brian T. Cunningham, Peter Y. Li, Frank DeFilippi
Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.
Type:
Application
Filed:
January 28, 2002
Publication date:
February 6, 2003
Applicant:
SRU Biosystems, LLC
Inventors:
Brian T. Cunningham, Jane Pepper, Bo Lin, Peter Li, Homer Pien, Jean Qiu
Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.
Type:
Application
Filed:
January 28, 2002
Publication date:
February 6, 2003
Applicant:
SRU Biosystems, LLC
Inventors:
Brian T. Cunningham, Jane Pepper, Bo Lin, Peter Li, Jean Qiu, Homer Pien
Abstract: Methods of producing liquid handling biosensor devices are provided. The liquid handling biosensor devices allow detection of biomolecular interactions in liquid. The use of labels is not required and the methods can be performed in a high-throughput manner.
Abstract: Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.
Type:
Application
Filed:
August 15, 2001
Publication date:
September 12, 2002
Applicant:
SRU Biosystems, LLC
Inventors:
Brian Cunningham, Jane Pepper, Bo Lin, Peter Li, Homer Pien