Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions.
Type:
Grant
Filed:
March 12, 2019
Date of Patent:
August 30, 2022
Assignee:
ST IP Holding AG
Inventors:
Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Jay Corey Bloom, Mark Joseph Kastantin
Abstract: This disclosure provides, among other things, compositions comprising quantities of oltipraz crystals, as well as method of making such compositions, and method of treating patients using such compositions. Taste-modified compositions also are provided.
Type:
Grant
Filed:
March 12, 2019
Date of Patent:
November 30, 2021
Assignee:
ST IP Holding AG
Inventors:
Anthony Chris Garland, Barbara-Jean Anne Bormann-Kennedy, Bomi Framroze, Bret Berner, Michael Edward Grass, Casey Keith Jager, Corey Jay Bloom, Mark Joseph Kastantin, Romain Bachelard
Abstract: This disclosure provides, among other things, formulated oltipraz compositions comprising stabilized oltipraz crystals, for use in treating a patient who has a viral infection or is at risk of incurring a viral infection. Such viral infections can include a viral infection caused by a coronavirus such as one associated with MERS or SARS, e.g., SARS-CoV-2.
Abstract: The invention provides improved methods of synthesizing oltipraz, which result in higher overall yield and better purity of the desired product.
Abstract: The invention provides improved methods of synthesizing oltipraz, which result in higher overall yield and better purity of the desired product.
Abstract: Described herein are formulations and methods for treating, managing, or preventing sleeplessness or restlessness, for increasing focus or concentration, or for decreasing anxiety. The formulations comprise honokiol and magnolol, which are present in magnolia bark extract, in admixture with one or more polyunsaturated fatty acids, such as those found in virgin salmon oil. As compared to other lipid formulations of honokiol and magnolol, the formulations show improved stability and increased uptake.
Abstract: The invention provides improved methods of synthesizing oltipraz, which result in higher overall yield and better purity of the desired product.