Patents Assigned to St. Vincent Medical Center
  • Patent number: 5848975
    Abstract: To optimize the .sup.14 C-urea breath test for Helicobacter pylori (a) a collection method for alveolar breath samples, (b) varying the post-dosage breath collection time and (c) varying the concentrations of KOH in the liquid trap employed for the capture of .sup.14 CO.sub.2 are employed. Collection of alveolar breath samples in bags was convenient for user and patient. The test provided optimal sensitivity and specificity for the detection of H. pylori infection when breath collections were performed 10 min after dosage with .sup.14 C-urea, and when breath CO.sub.2 was captured in liquid traps containing 80 or 800 mM KOH.
    Type: Grant
    Filed: September 29, 1997
    Date of Patent: December 15, 1998
    Assignee: St. Vincent's Medical Center of Richmond
    Inventor: Michael Phillips
  • Patent number: 5534506
    Abstract: The treatment of blood and other body fluids and tissues, the detection of tumors and the treatment of patients is disclosed. The treatment and detection involve the use of families of chlorins, families of purpurins and families of metal complexes of chlorins and purpurins. The purpurins and their metal complexes have the structures of FIGS. 1 , 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2 , 8, 19, 20, 22, 23, 24, 25, 27, 28, 39, 40, 42, 43 and 49-53 of the attached drawings. Solutions of the purpurins, of the foregoing and other chlorins and of the metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: July 9, 1996
    Assignees: University of Toledo, Medical College of Ohio, St. Vincent Medical Center
    Inventors: Alan R. Morgan, Steven H. Selman, Martha Kreimer-Birnbaum
  • Patent number: 5216012
    Abstract: Families of chlorins, families of purpurins and metal complexes thereof are disclosed. The purpurins and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2, 8, 19, 20, 22, 23, 24, 25, 27, 28, 39, 40, 42, 43 and 49-53 of the attached drawings. Solutions of the purpurins, of the foregoing and other chlorins and of the metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the purpurins, chlorins or metal complexes to the patient.
    Type: Grant
    Filed: September 23, 1991
    Date of Patent: June 1, 1993
    Assignees: University of Toledo, Medical College of Ohio, St. Vincent Medical Center
    Inventors: Alan R. Morgan, Steven H. Selman, Martha Kreimer-Birnbaum
  • Patent number: 5051415
    Abstract: Families of chlorins, families of purpurins and metal complexes thereof are disclosed. The purpurins and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of the attached drawings. The chlorins and their metal complexes have the formulas of FIGS. 2, 8, 19, 20, 22, 23, 24, 25, 27, 28, 39, 40, 42, 43 and 49-53 of the attached drawings. Solutions of the purpurins, of the foregoing and other chlorins and of the metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the purpurins, chlorins or metal complexes to the patient.
    Type: Grant
    Filed: August 2, 1989
    Date of Patent: September 24, 1991
    Assignees: The University of Toledo, Medical College of Ohio, St. Vincent Medical Center
    Inventors: Alan R. Morgan, Steven H. Selman, Martha Kreimer-Birnbaum
  • Patent number: 4641387
    Abstract: An enclosure for a bed to provide protection for patients who would have otherwise required soft restraints to prevent self injury. The enclosure is formed of a supporting framework and an associated covering provided with suitably arranged zippered areas for achieving access to the patient from the exterior of the enclosure.
    Type: Grant
    Filed: February 6, 1986
    Date of Patent: February 10, 1987
    Assignee: St. Vincent Medical Center
    Inventors: Daniel A. Bondy, Judith A. East, Christina M. Rizzo