Patents Assigned to Stabilitech Biopharma Ltd
  • Vaccine compositions
    Patent number: 10806783
    Abstract: The present invention relates to the use of an excipient which is a compound of formula (I) or a physiologically acceptable salt or ester thereof: wherein: R1 represents C1-6alkyl; R2 represents hydrogen or C1-6alkyl; and R3 represents C1-6alkyl, for increasing the immunogenicity of an influenza antigen, which use comprises (a) freezing, (b) heat-treating, and/or (c) freeze-drying an aqueous composition comprising the influenza antigen and the excipient.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: October 20, 2020
    Assignee: Stabilitech Biopharma Ltd
    Inventor: Jeffrey Drew
  • Excipients for stabilising viral particles, polypeptides or biological material
    Patent number: 10716859
    Abstract: A sterile pharmaceutically acceptable aqueous solution, which solution is provided in a sealed container and comprises: a pharmaceutically acceptable aqueous solvent; viral particles or a physiologically active polypeptide; an excipient selected from a polyethyleneimine; a compound of formula (I) or a physiologically acceptable salt or ester thereof; or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and optionally, one or more sugars.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: July 21, 2020
    Assignee: Stabilitech Biopharma Ltd
    Inventors: Jeffrey Drew, David Thomas Woodward, John Bainbridge, Amanda Corteyn
  • Stabilisation of viral particles
    Patent number: 10206960
    Abstract: A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating said viral particles.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: February 19, 2019
    Assignee: Stabilitech Biopharma Ltd
    Inventors: Jeffrey Drew, David Woodward, John Bainbridge, Amanda Corteyn
  • Vaccine compositions
    Patent number: 10086064
    Abstract: The present invention relates to the use of an excipient which is a compound of formula (I) or a physiologically acceptable salt or ester thereof: wherein: R1 represents C1-6alkyl; R2 represents hydrogen or C1-6alkyl; and R3 represents C1-6alkyl, for increasing the immunogenicity of an influenza antigen, which use comprises (a) freezing, (b) heat-treating, and/or (c) freeze-drying an aqueous composition comprising the influenza antigen and the excipient.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: October 2, 2018
    Assignee: Stabilitech Biopharma Ltd
    Inventor: Jeffrey Drew
  • Stabilisation of polypeptides
    Patent number: 10029007
    Abstract: A method for preserving a polypeptide comprising: (a) providing an aqueous solution of (i) the polypeptide, (ii) one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating the polypeptide.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: July 24, 2018
    Assignee: Stabilitech Biopharma Ltd
    Inventors: Jeffrey Drew, David Thomas Woodward, Stephen Ward