Patents Assigned to Stabilitech Ltd.
  • Method for preserving alum adjuvants and alum-adjuvanted vaccines
    Patent number: 9101607
    Abstract: A method for preserving an aluminium-salt adjuvant during freezing or drying comprising freezing or drying an aqueous suspension or solution comprising: (a) an aluminium salt adjuvant; (b) a compound of formula (I) or a physiologically acceptable salt or ester thereof or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (c) optionally, one or more sugars.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: August 11, 2015
    Assignee: Stabilitech Ltd.
    Inventors: Jeffrey Drew, David Woodward, Amanda Corteyn
  • STABILISATION OF POLYPEPTIDES
    Publication number: 20140294757
    Abstract: A method for preserving a polypeptide comprising: (a) providing an aqueous solution of (i) the polypeptide, (ii) one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating the polypeptide.
    Type: Application
    Filed: October 5, 2012
    Publication date: October 2, 2014
    Applicant: Stabilitech Ltd.
    Inventors: Jeffrey Drew, David Thomas Woodward, Stephen Ward
  • Method for Preserving Alum Adjuvants and Alum-Adjuvanted Vaccines
    Publication number: 20130156797
    Abstract: A method for preserving an aluminium-salt adjuvant during freezing or drying comprising freezing or drying an aqueous suspension or solution comprising: (a) an aluminium salt adjuvant; (b) a compound of formula (I) or a physiologically acceptable salt or ester thereof or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (c) optionally, one or more sugars.
    Type: Application
    Filed: March 31, 2011
    Publication date: June 20, 2013
    Applicant: Stabilitech Ltd.
    Inventors: Jeffrey Drew, David Woodward, Amanda Corteyn
  • Stabilisation of Viral Particles
    Publication number: 20130129685
    Abstract: A method for preserving viral particles comprising: (a) providing an aqueous solution of (i) viral particles, (ii) optionally one or more sugars, and (iii) a compound of formula (I) or a physiologically acceptable salt or ester thereof and/or a compound of formula (II) or a physiologically acceptable salt or ester thereof; and (b) drying the solution to form a composition incorporating said viral particles.
    Type: Application
    Filed: March 31, 2011
    Publication date: May 23, 2013
    Applicant: STABILITECH LTD.
    Inventors: Jeffrey Drew, David Woodward, John Bainbridge, Amanda Corteyn
  • Method for Preserving Polypeptides Using A Sugar and Polyethyleneimine
    Publication number: 20130071431
    Abstract: The invention relates to the preservation of an active agent, such as a polypeptide, by contacting the active agent with a preservation mixture including a sugar and polyethyleneimine.
    Type: Application
    Filed: November 13, 2012
    Publication date: March 21, 2013
    Applicant: Stabilitech Ltd.
    Inventor: Stabilitech Ltd.
  • Method for preserving viral particles
    Patent number: 8313897
    Abstract: A method for preserving viral particles comprises: (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said viral particles wherein the concentration of polyethyleneimine is 15 ?M or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said viral particles.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: November 20, 2012
    Assignee: Stabilitech Ltd.
    Inventor: Jeffrey Drew
  • Method for Preserving Polypeptides Using a Sugar and Polyethyleneimine
    Publication number: 20110236412
    Abstract: A method for preserving a polypeptide comprises (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said polypeptide wherein the concentration of polyethyleneimine is 25 ?M or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said polypeptide.
    Type: Application
    Filed: September 24, 2009
    Publication date: September 29, 2011
    Applicant: Stabilitech Ltd.
    Inventor: Jeffrey Drew
  • Method for Preserving Polypeptides Using a Sugar and Polyethyleneimine
    Publication number: 20110212127
    Abstract: The invention relates to the preservation of an active agent, such as a polypeptide, by contacting the active agent with a preservation mixture including a sugar and polyethyleneimine.
    Type: Application
    Filed: March 31, 2011
    Publication date: September 1, 2011
    Applicant: Stabilitech Ltd.
    Inventors: Jeffrey Drew, Stephen John Ward
  • Method for Preserving Viral Particles
    Publication number: 20100015177
    Abstract: A method for preserving viral particles comprises: (i) providing an aqueous solution of one or more sugars, a polyethyleneimine and said viral particles wherein the concentration of polyethyleneimine is 15 ?M or less based on the number-average molar mass (Mn) of the polyethyleneimine and the sugar concentration or, if more than one sugar is present, total sugar concentration is greater than 0.1 M; and (ii) drying the solution to form an amorphous solid matrix comprising said viral particles.
    Type: Application
    Filed: March 19, 2008
    Publication date: January 21, 2010
    Applicant: Stabilitech Ltd.
    Inventor: Jeffrey Drew
  • Desiccated Product
    Publication number: 20080152673
    Abstract: A desiccated or preserved product. The product comprises a sugar, a charged material and a sensitive biological component. The sugar forms an amorphous solid matrix.
    Type: Application
    Filed: February 9, 2006
    Publication date: June 26, 2008
    Applicant: Stabilitech Ltd.
    Inventor: Jeff Drew