Patents Assigned to Standen Ltd.
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Patent number: 8342487Abstract: Vehicle suspension comprising a pair of leaf springs (1) located or locatable on respective opposed side of a vehicle chassis (3) and extending longitudinally thereof, and an anti-roll device (12) which is arranged to extend transversely of the vehicle chassis (3), and means (41, 42, 46) mounting opposed ends (22, 23) of the anti roll device (12) rigidly to respective ones of the pair of opposed leaf springs (1).Type: GrantFiled: January 6, 2010Date of Patent: January 1, 2013Assignee: Standens Ltd.Inventor: John Bolland Reast
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Patent number: 8027738Abstract: An article of clothing is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The article of clothing includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells.Type: GrantFiled: June 14, 2006Date of Patent: September 27, 2011Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7917227Abstract: AC electric fields at particular frequencies and field strengths have been shown to be effective for destroying rapidly proliferating cells such as cancer cells. The effectiveness of such fields is improved when the field is sequentially switched between two or more different directions. The effectiveness of such fields can be improved even further by choosing the rate at which the field is switched between the various directions.Type: GrantFiled: September 29, 2006Date of Patent: March 29, 2011Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7912540Abstract: An article of clothing is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The article of clothing includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells.Type: GrantFiled: June 14, 2006Date of Patent: March 22, 2011Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7805201Abstract: Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results are obtained when the field is sequentially imposed in different directions.Type: GrantFiled: April 21, 2005Date of Patent: September 28, 2010Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7715921Abstract: As compared to conventional electrodes, the electrode configurations disclosed herein minimize irritation and damage to the skin when they are placed in contact with a patient's body over extended of time. The electrodes are formed from a conductive substrate coated with a thin dielectric material, and a plurality of open spaces pass through the electrodes. Those open spaces are distributed and sized to permit moisture on the surface of the patient's body to escape when the electrode is placed in contact with the patient's body. One intended use for the electrodes is for treating tumors by applying an AC electric field with specific frequency and field strength characteristics over an extended period of time.Type: GrantFiled: December 5, 2005Date of Patent: May 11, 2010Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7706890Abstract: An apparatus is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The apparatus includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The movement of the polarizable intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells, but does not damage non-dividing cells. In some embodiments, the electric field is guided to a desired target region by varying the sizes of the electrodes that are used to apply the electric field.Type: GrantFiled: March 7, 2005Date of Patent: April 27, 2010Assignee: Standen LtdInventor: Yoram Palti
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Patent number: 7599745Abstract: Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results are obtained when the field is sequentially imposed in different directions.Type: GrantFiled: April 21, 2005Date of Patent: October 6, 2009Assignee: Standen LtdInventor: Yoram Palti
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Patent number: 7599746Abstract: AC electric fields at certain frequencies and field strengths disrupt dividing cells, but leave undividing cells substantially unharmed. Since cancer cells divide much more often than normal cells, those AC fields have been shown to be effective at inhibiting tumor growth and shrinking tumors. Because certain body parts (e.g., the lungs and the liver) are at high risk for developing metastases in patients with some forms of cancer, treating those body parts with those AC fields can prevent metastases from growing in those body parts. This treatment may be used both after a metastasis has reached a detectable size and prophylactically (to prevent such metastases from ever reaching a detectable size in the first place). It may also be used to prevent cancer in people with a high probability of developing cancer (e.g., based on family history).Type: GrantFiled: June 7, 2006Date of Patent: October 6, 2009Assignee: Standen LtdInventor: Yoram Palti
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Patent number: 7565205Abstract: Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results are obtained when the field is sequentially imposed in different directions.Type: GrantFiled: April 21, 2005Date of Patent: July 21, 2009Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7565206Abstract: Cells that are in the late anaphase or telophase stages of cell division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like tumor cells, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results are obtained when the field is sequentially imposed in different directions. The field may also be rotated through 360° by applying AC waveforms with different phases to the electrodes.Type: GrantFiled: December 27, 2005Date of Patent: July 21, 2009Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7520517Abstract: A leaf spring assembly features a stack of leaf springs having mounting couplings attached at opposite ends. The mounting couplings each have first and second mounting elements clamped together about at least a main spring and a safety spring. The safety spring has retaining elements at opposite ends each having an extension portion and a blocking portion. The extension portion extends past the end of the main spring. Here the blocking portion extends generally perpendicularly from the extension portion to block motion of the mounting coupling should failure cause it to be detached from the stack of springs. This ensures that failure does not cause complete separation of the spring stack and mounting couplings.Type: GrantFiled: July 24, 2006Date of Patent: April 21, 2009Assignee: Standens Ltd.Inventors: Melvin Svendsen, Donald Stoesz, Marty Boll
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Patent number: 7519420Abstract: Dividing cells within living tissue that contain polarizable intracellular members can be destroyed using at least two insulated electrodes and an electric field source that applies an alternating electric potential across the conductors within the insulated electrodes. The electric field is transformed into a non-homogenous electric field that produces an increased density electric field in a region of the dividing cells. The non-homogenous electric field is of sufficient intensity to cause the intracellular members to be drawn to that region, which causes a pressure increase that results in a structural breakdown of the dividing cells.Type: GrantFiled: September 6, 2006Date of Patent: April 14, 2009Assignee: Standen LtdInventor: Yoram Palti
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Patent number: 7467011Abstract: An article of clothing is pro-vided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The article of clothing includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells.Type: GrantFiled: June 14, 2006Date of Patent: December 16, 2008Assignee: Standen LtdInventor: Yoram Palti
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Patent number: 7333852Abstract: The present invention provides a method and apparatus for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. According to the present method the living tissue is subjected to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogenous electric field being induced in the dividing cells. The non-homogenous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular members towards the cleavage furrow causes the break down thereof which results in destruction of the dividing cells, while the non-dividing cells of the living tissue remain intact.Type: GrantFiled: February 16, 2001Date of Patent: February 19, 2008Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7146210Abstract: The apparatus and method are designed to compute the optimal spatial and temporal characteristics for combating tumor growth within a body on the basis of cytological (as provided by biopsies, etc.) and anatomical data (as provided by CT, MRI, PET, etc.), as well as the electric properties of the different elements. On the basis of this computation, the apparatus applies the fields that have maximal effect on the tumor and minimal effect on all other tissues by adjusting both the field generator output characteristics and by optimal positioning of the insulated electrodes or isolects on the patient's body.Type: GrantFiled: March 28, 2003Date of Patent: December 5, 2006Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7136699Abstract: An apparatus is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The apparatus includes a generator and insulated electrodes for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular intracellular members towards the cleavage furrow causes the breakdown thereof which results in the destruction of the dividing cells, while the non-dividing cells of the living tissue remain intact.Type: GrantFiled: October 2, 2002Date of Patent: November 14, 2006Assignee: Standen, Ltd.Inventor: Yoram Palti
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Patent number: 7131501Abstract: U-shaped cushions, also known as shanks or spring members, resiliently support a gang of disks on the frame of a disk harrow. The agricultural disk cushion is manufactured from a round section of raw material which is lighter and more resistant to torsion related failure than traditional rectangular section shanks. Two leg portions are each tapered to have flat surfaces on opposite sides for flush fitting with mounting elements, while a central portion connecting them remains circular in cross section. The round cross section in this critical area can withstand severe omni-directional loading, as its resistance is equal in all directions The spring rate the leg portions of the disk cushion can be tailored individually to meet the requirements of the application.Type: GrantFiled: August 17, 2005Date of Patent: November 7, 2006Assignee: Standens Ltd.Inventors: Melvin Svendsen, Donald Stoesz, Simon Fen, Luc Jarry, Marty Boll
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Patent number: 7089054Abstract: An article of clothing is provided for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. The article of clothing includes insulated electrodes to be coupled to a generator for subjecting the living tissue to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogeneous electric field being induced in the dividing cells. The non-homogeneous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular intracellular members towards the cleavage furrow causes the breakdown thereof which adversely impacts the multiplication of the dividing cells.Type: GrantFiled: October 31, 2002Date of Patent: August 8, 2006Assignee: Standen Ltd.Inventor: Yoram Palti
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Patent number: 7016725Abstract: The present invention provides a method and apparatus for selectively destroying dividing cells in living tissue formed of dividing cells and non-dividing cells. The dividing cells contain polarizable intracellular members and during late anaphase or telophase, the dividing cells are connected to one another by a cleavage furrow. According to the present method the living tissue is subjected to electric field conditions sufficient to cause movement of the polarizable intracellular members toward the cleavage furrow in response to a non-homogenous electric field being induced in the dividing cells. The non-homogenous electric field produces an increased density electric field in the region of the cleavage furrow. The movement of the polarizable intracellular members towards the cleavage furrow causes the break down thereof which results in destruction of the dividing cells, while the non-dividing cells of the living tissue remain intact.Type: GrantFiled: November 5, 2002Date of Patent: March 21, 2006Assignee: Standen Ltd.Inventor: Yoram Palti