Patents Assigned to State Institute
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Patent number: 10676442Abstract: The present invention discloses a salt derivative of 1-(3-methanesulfonamidobenzyl)-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline. The salt derivative has a solubility in water of not less than 3.0 nmol/mL or 1.8 mg/mL. The salt derivative has a solubility in water of not less than 3.0 nmol/mL or 1.8 mg/mL.Type: GrantFiled: August 30, 2017Date of Patent: June 9, 2020Assignees: China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical IndustryInventors: Meihua Xie, Fuli Zhang, Taizhi Wu, Jialiang Zhong
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Patent number: 10428013Abstract: Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.Type: GrantFiled: June 25, 2012Date of Patent: October 1, 2019Assignees: Shanghai Institute of Phamaceutical Industry, China State Institute of Pharmaceutical IndustryInventors: Zhenpeng Yu, Gouping Wang, Zhen Zhang, Minyu Liu, Xiaoling Huang, Ying Liu, Lin Xiao, Li Cai, Xuejun Wu, Yifang Deng, Mianli Pan, Renhai Chen, Shenrong Tang, Quanhai Liu
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Publication number: 20140128463Abstract: Disclosed are amide compounds, preparation method and uses thereof, specifically, the compounds represented by formula I or pharmaceutically acceptable salts, wherein R1, R2, R3, R4, R5, Q, X and n are defined as in the description. Also disclosed are a method for preparing the compounds of formula I, a composition containing the compounds, and the uses of the same in the preparation of medicaments for regulating blood lipid and/or preventing gallstone. The compounds of formula I disclosed in the present invention have stability in vitro, good solubility in the pharmaceutical organic solvents and favorable bioavailability in animals.Type: ApplicationFiled: June 25, 2012Publication date: May 8, 2014Applicants: China State Institute of Pharmaceutic Industry, Shanghai Institute of Pharmaceutical IndustryInventors: Zhenpeng Yu, Gouping Wang, Zhen Zhang, Minyu Liu, Xiaoling Huang, Ying Liu, Lin Xiao, Li Cai, Xuejun Wu, Yifang Deng, Mianli Pan, Renhai Chen, Shenrong Tang, Quanhai Liu
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Patent number: 8346088Abstract: The inventions relate to a method for operating a controllable selective optical add/drop channel for fiber-optic communication system provided with 2N of wavelength-division multiplexing channels, whose optical frequencies are retunable at a constant frequency separations ?v between adjacent channels, with the aid of the inventive controllable optical add/drop multiplexers (70, 80, 90) that comprise multi-stage structures of optical filters ({75-i}, {85-i}, {95-i}), that are connected in different manner and provided with devices, for example electro-optical and thermo-optical phase shift devices, for controllable tuning the transmissions characteristics thereof. The optical filters are embodied in the form of single-stage (20), two-stage (40) and/or multi-stage (60) asymmetric Mach-Zehnder interferometers. The controllable optical add/drop multiplexer can be produced according to integrated optic technique in the form of monolithic solid-state device.Type: GrantFiled: November 29, 2005Date of Patent: January 1, 2013Assignees: Federal State Institution “FederalAgency for Legal Protection of the Results of Intellectual Activity with Military, Special and Dual Purposes”at the Ministry of Justice of Russian Federation, Vospi Center CISC (Closed Stock Company)Inventor: Vyacheslav Konstantinovich Sakharov
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Patent number: 7933717Abstract: The invention concerns the gyroscopic instrument engineering and can be used in determination of main navigation parameters for marine, air and surface vehicle positioning. Technical result consists in increased accuracy of output parameters, including substantial increase of the vehicle heading generation accuracy as well as principal improvement of dynamic properties of output parameter generation. To achieve these results control signals of gyro platforms or gyro platform models are generated under the condition that in the absence of ballistic deviations, autonomously, a natural period of the gyro platforms or the gyro platform models differ from Schuler period.Type: GrantFiled: December 21, 2005Date of Patent: April 26, 2011Assignees: Federal State Institution “Federal Agency for Legal Protection of Military, Special and Dual Use Intellectual Activity Results” under the Ministry of Justice of the Russian FederationInventor: Vladimir Aronovich Belenkiy
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Patent number: 7927566Abstract: The present invention relates to a treatment of high-level waste of radiochemical production containing radionuclides and macro-admixtures including sodium. The method of extraction of radionuclides by processing acidic aqueous waste solutions by extractants containing macrocyclic compounds selected from the group of crown ethers having aromatic fragments containing alkyl and/or hydroxyalkyl substituents of a linear and/or branched structure, and/or cyclohexane fragments containing alkyl and/or hydroxyalkyl substituents of a linear and/or branched structure, and/or fragments of —O—CHR—CH2O—, where R is the normal or branched alkyl or hydroxyalkyl in organic solvents containing polyfluorinated telomeric alcohol 1,1,7-trihydrododecafluoroheptanol-1 having the formula H(CF2CF2)nCH2OH, where n=3, and a mixture of polyoxyethylene glycol ethers of synthetic primary higher aliphatic alcohols of a fraction C12-C14 of a general formula CnH2n+1O(C2H4O)mH, where n=12-14, m=2 is proposed.Type: GrantFiled: September 9, 2004Date of Patent: April 19, 2011Assignees: Designing-Contructing and Industrial-Inculcating Enterprise “Daymos Ltd.”, Federal State Institute “Federal Agency for Legal Protection of Military Special and Dual Use, Intellectual Activity Results” under Ministry of Justice of the Russian Federation (FSI “FALPIAR”)Inventors: Jury Vasilievich Glagolenko, Mikhail Vasilievich Logunov, Igor Vitalievich Mamakin, Vladimir Mikhailovich Polosin, Sergey Ivanovich Rovny, Vadim Alexandrovich Starchenko, Jury Pavlovich Shishelov, Nikolay Gennadievich Yakovlev
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Patent number: 7867467Abstract: The invention relates to carbon chemistry and is embodied in the form of a nanodiamond comprising 90.0-98.0 mass % carbon, 0.1-5.0 mass % hydrogen, 1.5-3.0 mass % nitrogen and 0.1-4.5 mass % oxygen, wherein the carbon is contained in the form a diamond cubic modification and in a roentgen-amorphous phase at a ratio of (82-95):(18-5) in terms of a carbon mass, respectively. The inventive method for producing said material consisting in detonating in a closed space of a carbon-inert gas medium a carbon-containing oxygen-deficient explosive material which is placed in a condensed phase envelop containing a reducing agent at a quantitative ratio between said reducing agent mass in the condensed envelop and the mass of the used carbon-containing explosive material equal to or greater than 0.01:1 and in chemically purifying by treating detonation products with a 2-40% aqua nitric acid jointly with a compressed air oxygen at a temperature ranging from 200 to 280° C. and a pressure of 5-15 MPa.Type: GrantFiled: December 30, 2005Date of Patent: January 11, 2011Assignees: Federal State Institution “Federal Agency for Legal Protection of Military, Special and Dual Use Intellectual Activity Results” Under Ministry of Justics of the Russian Federation, Joint-Stock Company “Diamond Centre”Inventor: Valery Yurievich Dolmatov
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Patent number: 7836965Abstract: The object of the inventive method and device for controlling and/or extinguishing fires is to extend the range of means for transporting devices to a fire site, substantially reduce the time for the operating preparation thereof and to exclude a fragmentation field caused by the device explosion which ensures the momentary conversion of a fire-extinguishing composition into a fine cloud associated with a simultaneous airblast effect produced to a fire area and a maximum distribution of said fire-extinguishing composition through the fire volume. Said method for controlling and/or putting out a fire consists in effecting the fire area by an airblast and the high-speed flow of the air-dispersed mixture of the fire-extinguishing composition (7) produced by the explosion of a fire-suppressing device (2) which comprises a dispersing charge (8) and a container (6) with the fire-extinguishing composition (7).Type: GrantFiled: January 13, 2005Date of Patent: November 23, 2010Assignees: Federal State Unitary Enterprise State Research and Production Enterprise “Bazalt”, Federal State Institution Federal Agency for Legal Protection of Military, Special and Dual Use Intellectual Activity Results under Ministry of Justice of the Russian FederationInventors: Vladimir Vladimirovich Korenkov, Aleksei Andreevich Tereshin, Nikolai Andreevich Suprunov, Nikolai Konstantinovich Garnov, Vasily Nikolaevich Melkov, Vladimir Fedorovich Vlasov, Nikolai Petrovich Kopylov, Sergei Georgievich Tsarichenko
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Publication number: 20080014133Abstract: The present invention relates to a treatment of high-level waste of radiochemical production containing radionuclides and macro-admixtures including sodium. The method of extraction of radionuclides by processing acidic aqueous waste solutions by extractants containing macrocyclic compounds selected from the group of crown ethers having aromatic fragments containing alkyl and/or hydroxyalkyl substituents of a linear and/or branched structure, and/or cyclohexane fragments containing alkyl and/or hydroxyalkyl substituents of a linear and/or branched structure, and/or fragments of —O—CHR—CH2O—, where R is the normal or branched alkyl or hydroxyalkyl in organic solvents containing polyfluorinated telomeric alcohol 1,1,7-trihydrododecafluoroheptanol-1 having the formula H(CF2CF2)nCH2OH, where n=3, and a mixture of polyoxyethylene glycol ethers of synthetic primary higher aliphatic alcohols of a fraction C12-C14 of a general formula CnH2n+1O(C2H4O)mH, where n=12-14, m=2 is proposed.Type: ApplicationFiled: September 9, 2004Publication date: January 17, 2008Applicants: Design-Construction and Industrial-Innovation Enterprise, Ltd. "Daymos", Federal State Institution "Federal Agency for Legal Protection of Military, Special and Dual UseInventors: Jury Glagolenko, Mikhail Logunov, Igor Mamakin, Vladimir Polosin, Sergey Rovni, Vadim Starchenko, Jury Shishelov, Nikolay Yakovlev
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Publication number: 20010017260Abstract: An apparatus for electrolytic production of magnesium includes a plurality of upright anode elements interspread with a plurality of cathode elements situated within at least one electrolysis compartment. At least one section, defined between two adjacent anodes and having an elongated loading inlet, is provided for receiving and melting of a substantially solid raw material. A gas discharging outlet is formed for discharging of chlorine gas developed at the plurality of anodes. A baffle is supported by the receiving anodes in the vicinity of the gas discharging outlet. The baffle prevents direct flow of a mixture of chlorine gas and fine dust particles resulted from loading of the solid raw material between the section and gas discharging outlet.Type: ApplicationFiled: December 19, 2000Publication date: August 30, 2001Applicant: State InstituteInventors: Igor V. Zabelin, Georgy M. Shehovtsov, Vladimir N. Deviatkin, Irina L. Sikorskaya, Alexander M. Tatakin, Tatiana V. Zabelina