Patents Assigned to State of Oregan, Acting by and Through the Oregon State Board of Higher Education on Behalf of the Oregon Health Sciences University
  • Methods for treating circadian rhythm phase disturbances
    Patent number: 5591768
    Abstract: A method for treating circadian rhythm phase disorders is described. The invention provides methods to specifically advance or delay the phase of certain circadian rhythms in humans. The disclosed methods relate to the administration of melatonin at times determined with relation to the time of dim light endogenous melatonin onset. Embodiments capable of alleviating the effects of jet lag, winter depression and shift-work sleep disturbance are provided.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: January 7, 1997
    Assignee: State of Oregan, Acting by and Through the Oregon State Board of Higher Education on Behalf of the Oregon Health Sciences University
    Inventors: Alfred J. Lewy, Robert L. Sack