Patents Assigned to State University
  • RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING BY TRACKING SUB-MICRON SCALE MOTION OF SINGLE BACTERIAL CELLS
    Publication number: 20200172951
    Abstract: A method for rapid antibiotic susceptibility testing by tracking sub-micron scale motion of single bacterial cells including obtaining a biological sample from a subject including live bacteria. Different doses of antibiotic are added to a multi-well glass slide and adding portions of the biological sample to the wells. Bacterial cells are tethered onto the surface. The tethered bacterial cells are imaged and tracked. Bacterial sub-micron motion of tethered cells is measured at the different doses. A processor performs statistical analysis on a population of cells for each antibiotic dose to generate an antibiotic dose curve proportional to the motion changes, where the antibiotic dose curve plots data including a decrease in movement over time indicating a proportional effectiveness of an antibiotic applied to a well.
    Type: Application
    Filed: July 25, 2018
    Publication date: June 4, 2020
    Applicant: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Nongjian Tao, Karan Syal
  • PIEZOELECTRIC-TRIBOELECTRIC HEEL CHARGER TO GENERATE ELECTRICITY FROM LOCOMOTION USING LEVEL MECHANISM AND MECHANICAL SSHI BOOSTING CIRCUIT
    Publication number: 20200177105
    Abstract: The disclosure provides an electricity generating insert for a piece of footwear, the insert can be removably placed in the heel portion, e.g. under the insole. The insert comprises a multilayer piezoelectric stack that alternatively flexes under the compression-decompression that occurs during locomotion, which flexing causes friction in the stack to generate electricity capable of charging electronic devices and the like, e.g. via a port on the footwear.
    Type: Application
    Filed: November 8, 2019
    Publication date: June 4, 2020
    Applicant: The Research Foundation for The State University of New York
    Inventors: Ya Wang, Haili Liu
  • Dialysis system
    Patent number: 10668201
    Abstract: A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: June 2, 2020
    Assignees: Oregon State University, Outset Medical, Inc.
    Inventors: Julie S. Wrazel, James R. Curtis, Ladislaus Nonn, Richard B. Peterson, Hailei Wang, Robbie Ingram-Goble, Luke W. Fisher, Anna E. Garrison, M. Kevin Drost, Goran Jovanovic, Richard Todd Miller, Bruce W. Johnson, Alana Anderson, Eric K. Anderson
  • (S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using
    Patent number: 10667515
    Abstract: (S)-5-ethynyl-anabasine and derivatives thereof; composition comprising same and a carrier; methods of treating an animal; method of protecting a plant from a pest; and methods of making compound and derivatives.
    Type: Grant
    Filed: July 16, 2017
    Date of Patent: June 2, 2020
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Richard J. Martin, Alan P. Robertson, Brett VanVeller, Xiangwei Du, Fudan Zheng
  • Multi-band multi-mode software defined radio
    Patent number: 10673469
    Abstract: A multi-band, multi-mode software defined radio (MBMM SDR) platform having a multi-band front end (MBFE), a multi-mode digital radio (MMDR), a configuration & control (C2) subsystem, and a power distribution subsystem. The MBFE provides wideband operations, L/S/C-Band telemetry band selection, and channel tuning. The MMDR provides high-speed signal processing and flexible programming to support multiple telemetry waveforms that are implemented using system-on-chip technology. An integrated pulse code modulation/frequency modulation (PCM/FM) and shaped offset quadrature shift keying (SOQPSK-TG) transmitter and a non-coherent PCM/FM receiver has been developed. The C2 subsystem allows for pre-test configuration and control of the MBFE and MMDR subsystems.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: June 2, 2020
    Assignee: Morgan State University
    Inventors: Willie L Thompson, II, Samuel Berhanu, Jan-Paul Alleyne
  • Compositions and uses for treatment thereof
    Patent number: 10669542
    Abstract: The invention is directed generally to oligonucleotide compositions for the treatment of DNA repeat expansion diseases. The invention also relates to oligonucleotides directed to subunits of the DNA mismatch repair system.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: June 2, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Edward L. Grabczyk, Kayla T. Fuselier
  • Nanocaged enzymes with enhanced catalytic activity and increased stability
    Patent number: 10669534
    Abstract: The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: June 2, 2020
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jinglin Fu, Zhao Zhao, Neal Woodbury, Hao Yan
  • Conductive self-healing network
    Patent number: 10669399
    Abstract: Disclosed herein are self-healing conductive network compositions. The networks can contain one or more conductive polymers and one or more supramolecular complexes. The supramolecular complex can be introduced into conductive polymer matrix, resulting in a network of the two components. In this network, the nanostructured conductive polymer gel constructs a 3D network to promote the transport of electrons and mechanically reinforce the network while the supramolecular complex contributes to self-healing property and also conductivity. The networks disclosed herein are useful for various applications such as self-healing electronics, artificial skins, soft robotics and biomimetic prostheses.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: June 2, 2020
    Assignees: Board of Regents, The University of Texas System, Texas State University
    Inventors: Guihua Yu, Ye Shi, Xiaopeng Li
  • Poly(thioethers) for metal ion sequestration
    Patent number: 10669378
    Abstract: The invention provides a polymer comprising two or more residues of formula III or IV or salts thereof: wherein dash line, X, Y, Q, L, M, n, R1, R2, Ra, Rb, Rc and Rd have any of the values defined in the specification, as well as synthetic intermediates and synthetic methods useful for preparing the compounds. The polymer is useful to treat contaminated water by chelating metal.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: June 2, 2020
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Agostino Pietrangelo, Anshuman Mangalum
  • Treating cancer with drug combinations
    Patent number: 10668068
    Abstract: Embodiments of the invention find application in the field of cancer therapy. Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: June 2, 2020
    Assignee: The Research Foundation For The State University Of New York
    Inventors: Xianhui Wang, Douglas S. Conklin
  • Framework for security strength and performance analysis of machine learning based biometric systems
    Patent number: 10671735
    Abstract: A framework for measuring the security strength of bio-metric security systems against spoofing attacks considering the adversary's knowledge about the system is disclosed.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: June 2, 2020
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Sandeep K. S. Gupta, Ayan Banerjee, Seyed Koosha Sadeghi Oskooyee, Mohammad Javad Sohankar Esfahani
  • Quantification of inflammatory molecules in exhaled breath condensate using differential pulse voltammetry on reduced graphene oxide sensor
    Patent number: 10670580
    Abstract: A device for detecting a biomarker for inflammation in a respiratory system includes a sample collection and/or holding area to receive an exhaled breath condensate (EBC) sample obtained from a respiratory system; an electrode system coupled to the sample collection area, the electrode system including reduced graphene oxide (rGO); and circuitry coupled to the electrode system. The circuitry is configured to apply a voltage to the EBC sample in the sample collection area via the electrode system and to measure a current via the electrode system in response to the voltage applied, in order to determine a concentration of nitrite in the EBC sample based on the current measured. The concentration of nitrite is a biomarker for inflammation in the respiratory system.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: June 2, 2020
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Mehdi Javanmard, Azam Gholizadeh, Manish Chhowalla, Robert J. Laumbach, Howard M. Kipen, Clifford P. Weisel, Andrew J. Gow, Damien Voiry
  • System and method to discover device context and location using cellular signal information
    Patent number: 10674474
    Abstract: System and method for receiving a plurality of cellular signals, determining a plurality of context data including at least one of an action data and a location data, mapping the plurality of cellular signals to the plurality of context data, generating a plurality of context signatures based on the mapping of the plurality of cellular signals to the plurality of context data, storing the plurality of context signatures, and determining a context profile associated with the communication device at an instance using a probability distribution of the stored plurality of context signatures.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: June 2, 2020
    Assignee: North Carolina State University
    Inventors: Nithyananthan Poosamani, Injong Rhee
  • Combinatorial therapies for the treatment of neoplasias using the opioid growth factor receptor
    Patent number: 10668126
    Abstract: The present invention relates to pharmaceutical compositions for treating neoplasias in an animal or human comprised of a carrier and therapeutically effective amounts of at least one chemotherapeutic agent along with the biotherapeutic endogenous pentapeptide Met-enkephalin, referred to as opioid growth factor. Also provided are methods of treating neoplasias in an animal or human in need of such treatment, comprising the administration to the animal or human therapeutically effective amounts of a pharmaceutical composition comprised of a carrier and therapeutically effective amounts of at least one neoplasia-treating agent, such as a chemotherapeutic agent or radiation, along with opioid growth factor.
    Type: Grant
    Filed: February 21, 2005
    Date of Patent: June 2, 2020
    Assignee: The Penn State University Research Foundation
    Inventors: Ian S. Zagon, Patricia J. McLaughlin, Jill P. Smith
  • Hybrid diamond-polymer thin film sensors and fabrication method
    Patent number: 10667709
    Abstract: An implantable device is provided. The implantable device includes a flexible polymeric substrate that extends through an aperture in an electrically conductive material to form an anchor that partially covers the electrically conductive material. Methods for fabricating the implantable device are also provided.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: June 2, 2020
    Assignees: Board of Trustees of Michigan State University, Fraunhofer USA
    Inventors: Wen Li, Bin Fan, Robert Rechenberg, Michael Becker, Cory Rusinek
  • Compact spectrometer focusing apparatus
    Patent number: 10672529
    Abstract: A spectrometer focusing apparatus is provided that includes a hollow cylinder for x-rays to traverse a length thereof, a defracting element configured as a ring on an interior circumference of a portion of the hollow cylinder, at least one disk having an edge defining a circle aligned with the defracting element, and an aperture formed between the defracting element and the edge of the at least one disk.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: June 2, 2020
    Assignee: The Research Foundation for The State University of New York
    Inventor: Paul Northrup
  • Compounds for inhibiting bacterial growth via phosphatidylglycerol binding
    Patent number: 10668048
    Abstract: Antibacterial small molecule compounds, termed liptins, bind to phosphatidylglycerol in bacterial plasma membranes. The small molecule compounds comprise a three-dimensional complementary binding pocket for phosphatidylglycerol, disrupting membrane function in a bacteriostatic or bactericidal manner. Methods of inhibiting bacterial growth and/or treating Gram-positive or Gram-negative bacterial infection using such compounds are also disclosed.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: June 2, 2020
    Assignee: Wichita State University
    Inventors: Dennis H. Burns, Douglas S. English
  • High sensitivity method for early Lyme disease detection
    Patent number: 10669567
    Abstract: The present disclosure provides methods for detecting early Lyme disease. The present disclosure provides a biosignature indicative of the presence or absence of Borrelia burgdorferi infection.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: June 2, 2020
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Colorado State University Research Foundation, New York Medical College
    Inventors: John T. Belisle, Claudia R. Molins, Gary P. Wormser
  • Adapter for finger appendage of brass instrument
    Patent number: 10672369
    Abstract: An adapter for the finger appendage of a brass instrument has an adapter body. An outboard side and an inboard side of the adapter body are spaced apart along a width. The adapter includes a fitting portion defining the outboard side of the adapter body and a spacer portion defining the inboard side of the adapter body. The fitting portion defines a mounting opening configured to receive the first portion of the adapter body to mount the adapter body on the finger appendage such that the spacer portion is received in the finger gap and the inboard side of the adapter body opposes the second portion of the finger appendage to define a reduced gap having a width that is less than the width of the finger gap.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: June 2, 2020
    Assignee: Wichita State University
    Inventor: John Hunsicker
  • Sweetpotato plant named ‘NCORNSP-024SCRI’
    Patent number: PP31837
    Abstract: ‘NCORNSP-024SCRI’ is a compact, non-twining, upright variety producing many short shoots. It is distinguishable from other cultivars by its purple palmate shaped leaves with a lobed base; a compact habit and semi-erect mounding plant architecture. The purple leaves, short internodes, and the plant architecture are what makes ‘NCORNSP-024SCRI’ unique amongst the current ornamental sweetpotatoes in the marketplace. ‘NCORNSP-024SCRI’ also exhibits very good vigor and is well branched.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: June 2, 2020
    Assignee: North Carolina State University
    Inventors: George Craig Yencho, Kenneth Vincent Pecota, Meri K. Reeber, Dominic Alexander Gillooly