Abstract: A wedge osteotomy device including a cutting guide coupled to a base plate via a joint. The cutting guide configured to pivot relative to the base plate about a pivot axis extending through the joint. The cutting guide including a guide body including a cutting slot extending through the guide body, an arcuate slot extending through the guide body and defining a radius to the joint, and a plurality of markers on the guide body identifying a position of the cutting guide relative to the base plate. The base plate including planar top and bottom surfaces.

Abstract: A subsurface monitoring system and method is provided that includes a sensor array and a monitoring system in communication with the array. The sensor array may include several sensors, such as subsurface temperature sensors, water-level sensors, and oxidation reduction potential sensors may be disposed in a vertical and/or horizontal fence through the subsurface of the monitored site. The sensor array may measure, collect, and analyze the subsurface conditions and provide the measurements to a monitoring system. The monitoring system may provide access the measurements via a user interface for analysis of the measurements. In addition, the monitoring system may process the measurements to generate one or more graphs of information for better understanding of the conditions of the subsurface of the monitored site.

Abstract: A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.

Abstract: Materials and methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.

Abstract: Provided herein are affinity reagents having affinity for particular target, each reagent having a unique DNA barcode, and methods for using the same to measure the abundance of targets in a sample. In particular, methods are provided in which unique barcodes linked to affinity reagents are contacted to a sample to bind antigens if present in said sample. In cases in which the affinity reagents are antibodies and the targets are antigens, antibodies that are bound to their target antigens can be separated from unbound antibodies and the DNA barcode associated with the affinity reagent is amplified, such as with a PCR reaction. In some cases, amplified barcode DNA is subjected to DNA sequencing as a measure of the levels of the target protein in the sample.

Abstract: Valproate is useful as an antifungal agent. The valproate compositions can be used to treat fungal infections. The valproate compositions can be formulated as topical antifungals.

Abstract: A thermal receiver, such as a solar flux thermal receiver, is disclosed comprising a modular arrangement of arrayed microchannels or micropins to heat a working fluid by heat transfer. Disclosed solar receivers provide a much higher solar flux and consequently a significant reduction in thermal losses, size, and cost, relative to known receivers. Unit cell receivers can be numbered up and combined in parallel to form modules, and modules combined to form full scale receivers.

Abstract: An alloy and method for producing an alloy is presented. The Titanium alloy has Ti-xCr-yFe-zAl, where 16>x>10, 4>y>0, and 6>z>0, where the alloy is subjected to strain at a temperature between 250 and 500 degrees C. A portion of the Titanium alloy is converted from a first phase to a second phase.

Abstract: Thermoelectric materials based on tetrahedrite structures for thermoelectric devices and methods for producing thermoelectric materials and devices are disclosed. The thermoelectric device has a pair of conductors and a p-type thermoelectric material disposed between the conductors. The thermoelectric material is at least partially formed of a hot pressed high energy milled tetrahedrite formed of tetrahedrite ore and pure elements to form a tetrahedrite powder of Cu12-xMxSb4S13 disposed between the conductors, where M is at least one of Zn and Fe.

Abstract: Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioesterase enzymes. Also disclosed are compositions comprising thioesters produced by the methods disclosed herein.

Abstract: Provided are an apparatus and method for two-dimensional spectroscopy using frequency combs and optical resonators, with the apparatus including at least one cavity and a controller for controlling generating a pump excitation using at least two frequency combs, generating a probe excitation using at least one frequency comb, and generating a resonantly enhanced signal frequency comb via a nonlinear-optical response of the sample. All frequency combs are resonant with a transverse mode of the cavity, to generate cavity-enhanced two-dimensional spectroscopy signals.

Abstract: Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS.

Abstract: Disclosed herein are embodiments of a microscale-based device suitable for purifying fluid, and method of using the device. In particular disclosed embodiments, an electrode layer comprising an enhanced surface area electrode material that has multiple extensions covered in a conductive material are used within the device. The device comprises one or more main flow pathways and one or more side channels. The flow dynamics of the device may be controlled in order to remove contaminants from the fluid. The extensions of the enhanced surface area electrode material are positioned on the surface of the pathways and also may be positioned within the side channels.

Abstract: A method for gas atomization of oxygen-reactive reactive metals and alloys wherein the atomized particles are exposed as they solidify and cool in a very short time to multiple gaseous reactive agents for the in-situ formation of a protective reaction film on the atomized particles. The present invention is especially useful for making highly pyrophoric reactive metal or alloy atomized powders, such as atomized magnesium and magnesium alloy powders. The gaseous reactive species (agents) are introduced into the atomization spray chamber at locations downstream of a gas atomizing nozzle as determined by the desired powder or particle temperature for the reactions and the desired thickness of the reaction film.

Abstract: In one embodiment, a system and method for assisting a physician with a hospital discharge decision pertain to collecting patient data from a patient under consideration who is staying at a hospital, estimating a mathematical probability of the patient under consideration being readmitted to the hospital within a predetermined amount of time if the patient under consideration were discharged on that day, wherein the mathematical probability estimate is based upon the collected patient data and patient data collected from a population of former hospital patients who had previously been discharged and whose readmission status is known, and providing information to the physician that assists the physician in deciding whether or not to discharge the patient under consideration, the information being based upon the results of the mathematical probability estimate.

Abstract: A virtual reality (VR) system includes a light source configured to illuminate an area and a plurality of photosensors configured to receive reflections from the illuminated area. The system includes a trained orientation module configured to store a trained neural network model and a gaze direction identification module coupled to the light source and the plurality of photosensors. The gaze direction identification module includes a light reflection module configured to receive a light intensity value from each of the plurality of photosensors and an eye coordinate determination module configured to apply the trained neural network model to the light intensity value from each of the plurality of photosensors to determine a horizontal coordinate value and a vertical coordinate value. The system includes a display configured to adjust a displayed image based on the gaze position of the illuminated area.

Abstract: An optical beam transformer includes a taper structure where the structure width is varied, an integrated aspherical semi-lens structure having a straight proximal end formed adjacent to a distal end of the taper structure to be in direct contact therewith, and a convex semi-lens section having a curved proximal end in direct contact with a curved distal end of the integrated aspherical semi-lens structure.

Abstract: Robotic platforms and methods of use are disclosed that include: at least one robot or robotic device, at least one computer-based control system, wherein the system is at least in part located on the at least one robot, at least one communications system, wherein the communications system is designed to communicate between the computer-based control system and the at least one robot, and at least one evaluation system that is designed to implement and process at least one nondestructive testing method.

Abstract: This invention is directed to a method of diagnosing bladder cancer in dogs.

Abstract: Aspects disclosed in the detailed description include memory compression in a deep neural network (DNN). To support a DNN application, a fully connected weight matrix associated with a hidden layer(s) of the DNN is divided into a plurality of weight blocks to generate a weight block matrix with a first number of rows and a second number of columns. A selected number of weight blocks are randomly designated as active weight blocks in each of the first number of rows and updated exclusively during DNN training. The weight block matrix is compressed to generate a sparsified weight block matrix including exclusively active weight blocks. The second number of columns is compressed to reduce memory footprint and computation power, while the first number of rows is retained to maintain accuracy of the DNN, thus providing the DNN in an efficient hardware implementation without sacrificing accuracy of the DNN application.