Abstract: The present disclosure relates to Quinstatin compounds, pharmaceutical compositions comprising such compounds, kits, and methods for using such compounds or pharmaceutical compositions.

Abstract: Power converter circuitry includes a direct current (DC) input comprising a first DC input node and a second DC input node, an alternating current (AC) output comprising a first AC output node coupled to the first DC input node and a second AC output node, a first boost switch coupled between the second DC input node and a boost intermediate node, a second boost switch coupled between the boost intermediate node and a common node, a boost inductor coupled between the boost intermediate node and the first DC input node, a link capacitor coupled between the second DC input node and the common node, a first half-bridge switch coupled between the second DC input node and a half-bridge intermediate node, a second half-bridge switch coupled between the half-bridge intermediate node and the common node, and a half-bridge inductor coupled between the half-bridge intermediate node and the second AC output node.

Abstract: Selective recovery of C2 to C4 hydrocarbons is achieved through the use of a converging-diverging nozzle, or de Laval nozzle. The vapor stream comprising C2 to C4 hydrocarbons is fed into an inlet of a de Laval nozzle having a throat. The vapor stream may have an initial temperature of between 0° C. and 100° C., and an initial pressure of between 200 psig and 500 psig. In the de Laval nozzle, the vapor stream expands after passing through the throat of the de Laval nozzle, producing a vapor stream having reduced temperature and pressure. Then, C2 to C4 hydrocarbons condense from the reduced-temperature vapor stream as liquid droplets, which may be recovered. Fractionation of C2 to C4 hydrocarbons by means of a de Laval nozzle is possible; the technique allows selective recovery of propane from a mixture of propane and ethane.

Abstract: A method of generating one of podocyte progenitor cells and neural stem/progenitor cells comprising the steps of collecting a urine specimen from a patient; centrifuging the urine specimen; and removing the one of podocyte progenitor cells and neural stem/progenitor cells.

Abstract: Eight new sweet basil (Ocimum basilicum L.) cultivars designated ‘Rutgers Thunderstruck-DMR’, ‘Rutgers Passion-DMR’, Rutgers Obsession-DMR’, ‘Rutgers Devotion-DMR’, ‘26_24_33’, ‘50_03_05’, ‘50_03_34’, and ‘42_21_02’ are provided, as are parts of the plants, extracts and biomasses from the variety, and uses thereof, for example as a food or in a food product. These plants have basil downy mildew resistance/tolerance.

Abstract: A digital signal synthesizer for generating a frequency and/or phase modified digital signal output comprises an input buffer, a transform module, a processing module, and an output buffer. The input buffer receives a digital input that is represented in a frequency domain representation. The transform module stores a fractional order control system that models a desired frequency and/or phase response defined by an assembly of at least one filter component. Each filter component is defined by a Laplace function that is modified to include a non-integer control order having a variable fractional scaling exponent. The processing module multiplies or divides the digital input with the fractional order control system stored in the transform module. Moreover, the output buffer stores a synthesized output of the input, which is modified in the frequency domain, the phase domain, or both according to the desired frequency and/or phase response by the processing module.

Abstract: Embodiments of a sustainable self-cooling framework for processors using thermoelectric generators that power an arrangement of thermoelectric coolers to reduce the temperature of thermal hot spots generated by a processor are disclosed.

Abstract: An internal combustion engine includes a pre-chamber. In another aspect, pressure within a pre-chamber is equal to or greater than pressure within a main combustion chamber at least prior to ignition in the main combustion chamber. In yet another aspect, internal combustion engine control software automatically controls pressure within a turbulent jet ignition pre-chamber, controls a valve-actuator to admit a fuel-air charge into the pre-chamber, and causes an igniter to initiate combustion in the pressurized pre-chamber. This also permits the rate of combustion to be controlled in the primary chamber regardless of the air-fuel ratio or the diluent fraction in the main chamber. Another aspect employs a pre-chamber purge pump with separate air and fuel injection.

Abstract: Provided are antisense oligomers targeted against bacterial mRNAs and other macromolecules associated with a biochemical pathway and/or cellular process, and related compositions and methods of using the oligomers and compositions to treat an infected mammalian subject, for example, as primary antimicrobials or as adjunctive therapies with classic antimicrobials.

Abstract: Multi-modal stimulation therapy may be utilized in which two or more stimulation therapies having different stimulation parameters may be delivered to a single patient. This can preferentially stimulate different nerve fiber types and drive different functional responses in the target organs. The stimulation parameters that may vary between the different stimulation therapies include, for example, pulse frequency, pulse width, pulse amplitude, and duty cycle.

Abstract: Xerogels and compositions comprising xerogels comprising a transition metal oxide and silicon oxide xerogel matrix. The xerogels and compositions can be made from mixtures of transition metal alkoxide(s) and tetraalkoxysilane(s) and, optionally, alkyltrialkoxysilane(s), aminoalkyl-, alkylaminoalkyl-, dialkylaminoalkyltrialkoxysilane(s), or a combination thereof. The xerogels and compositions can be used as antifouling coatings on, for example; boats.

Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).

Abstract: The present invention provides a biocompatible conjugate for treating a disease or an injury. The conjugate contains a polymer covalently linked to one or more moieties each containing a polymerizable functional group. The conjugate forms a cross-linked polymer network after being exposed to an elevated level of free radicals associated with the disease or injury.

Abstract: Aspects of the present disclosure involve systems, methods, and computer program products for obtaining and displaying a large image file over a network. In one embodiment, a user utilizes a computing device to obtain a large image file over a network, such as the Internet. The large image file may be stored in and available from a network device, such as an application server or database. To obtain the image file, a user interface executed on the user's computing device determines which portions of the overall image file are to be displayed in the interface. The interface may utilize one or more image variables to create or generate one or more network addresses at which the image tiles are stored or otherwise available. To retrieve the image tiles, the computing device uses the generated network addresses of the identified image tiles to request and obtain the image tiles.

Abstract: A method and system for treating cardiac arrhythmias which includes inserting one or more electrodes into a patient's neck, and connecting the electrodes to the vagus nerve in the patient's neck. A cardiac monitoring device detects a cardiac arrhythmia. A controller connected to an electrical power source provides electrical power to the electrodes to apply electrical stimulation to the vagus nerve when a cardiac arrhythmia is detected.

Abstract: Gang migration refers to the simultaneous live migration of multiple Virtual Machines (VMs) from one set of physical machines to another in response to events such as load spikes and imminent failures. Gang migration generates a large volume of network traffic and can overload the core network links and switches in a datacenter. In this paper, we present an approach to reduce the network overhead of gang migration using global deduplication (GMGD). GMGD identifies and eliminates the retransmission of duplicate memory pages among VMs running on multiple physical machines in the cluster. The design, implementation and evaluation of a GMGD prototype is described using QEMU/KVM VMs. Evaluations on a 30-node Gigabit Ethernet cluster having 10GigE core links shows that GMGD can reduce the network traffic on core links by up to 65% and the total migration time of VMs by up to 42% when compared to the default migration technique in QEMU/KVM.

Abstract: Disclosed herein are methods of connecting disrupted tissue, tissue repair, treating colorectal disorder and tissue welding. The methods comprise using a bioadhesive composition comprising ELP and light absorbing chromophores and irradiating the bioadhesive tissue.

Abstract: For textured digital elevation model generation, a method projects swath point projection coordinates of each lidar point of texel swaths into a corresponding texel swath with normalized projection coordinates. Each texel swath includes lidar points, an optical image, and swath output projection point coordinates of the lidar points into the optical image. The method generates a projection matrix including lidar point data for each lidar point of each texel swath. The method calculates enhanced lidar coordinates for each lidar point as a function of minimizing misregistration errors. In addition, the method creates enhanced output pixel coordinates for each image pixel based on the enhanced lidar coordinates for the lidar points and the associated output pixel coordinates. The method generates a textured digital elevation model based on the enhanced output pixel coordinates for each image pixel, and the enhanced lidar coordinates.

Abstract: Polaritonic hot electron infrared photodetector that detect infrared radiation. In one implementation, the polaritonic hot electron infrared photodetector includes a first contact layer, a second contact layer, a first dielectric layer, a second dielectric layer, and a conductor layer. The first dielectric layer is coupled between the first contact layer and the second contact layer. The second dielectric layer is coupled between the first dielectric layer and the second contact layer. The conductor layer is coupled between the first dielectric layer and the second dielectric layer. Infrared radiation incident upon the conductor layer is operable to create hot carriers that are injected from a conduction band of the conductor layer to a conduction band of the second contact layer.

Abstract: A new and distinct peach variety of Prunus persica named ‘NJ357’ is provided. This variety is distinguished from other peach varieties by its unique combination of showy flowers, large, nearly round, freestone fruit, with an attractive red blush and orange-red mottle over a bright yellow-orange ground color, ripening in midseason, with yellow-orange, firm, juicy flesh, and sweet, subacid flavor that is maintained following cold storage.