Patents Assigned to State University
  • Aminoglycoside and azole compositions and methods
    Patent number: 9669044
    Abstract: The present invention relates to novel fungicidal compound including an aminoglycoside analog having certain substituents at the 6 position of ring III that exhibit improved antifungal activity but possess minimal antibacterial properties in combination with fungicidal azoles. The aminoglycoside compounds are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: June 6, 2017
    Assignee: Utah State University
    Inventors: Jon Y. Takemoto, Cheng-wei Tom Chang, Sanjib K. Shrestha, Michelle Grilley
  • Thermoelectric materials based on tetrahedrite structure for thermoelectric devices
    Patent number: 9673369
    Abstract: Thermoelectric materials based on tetrahedrite structures for thermoelectric devices and methods for producing thermoelectric materials and devices are disclosed.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: June 6, 2017
    Assignees: Board of Trustees of Michigan State University, The Regents of the University of California
    Inventors: Donald T. Morelli, Xu Lu, Vidvuds Ozolins
  • Phosphorescent tetradentate metal complexes having modified emission spectra
    Patent number: 9673409
    Abstract: Multidentate metal complexes useful as phosphorescent emitters in display and lighting applications having the following structures:
    Type: Grant
    Filed: June 10, 2014
    Date of Patent: June 6, 2017
    Assignees: Arizona Board of Regents on behalf of Arizona State University, Universal Display Corporation
    Inventors: Jian Li, Guijie Li, Jason Brooks
  • Tongue stimulation for communication of information to a user
    Patent number: 9669159
    Abstract: Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be placed entirely within a mouth of the user and atop the tongue of the user. An array of electro-tactile elements may be distributed on the body, wherein each of the electro-tactile elements is configured to stimulate an area of the tongue adjacent the electro-tactile element. A wireless receiver coupled to the body may be configured to receive stimulation information wirelessly from outside the mouth of the user. At least one processing unit coupled to the body may be configured to transform the received stimulation information into a stimulation signal for each of the electro-tactile elements, and to provide the stimulation signals to the electro-tactile elements.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: June 6, 2017
    Assignee: Colorado State University Research Foundation
    Inventors: John D. Williams, Joel A. Moritz, Charles S. Henry, Steven D. Floyd, Luke T. Van, Kendall Gurule, Jaclyn A. Adkins, Matthew J. Swigart, Travis S. Bailey, Leslie M. Stone-Roy
  • Methods and devices for DNA sequencing and molecular diagnostics
    Patent number: 9670540
    Abstract: The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further directed to a device comprising a solid support having a plurality of wells or pillars and a plurality of oligonucleotides attached to the wells or pillars. Other aspects of the invention are directed to methods of making such devices.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: June 6, 2017
    Assignees: Cornell University, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Francis A. Barany, Steven A. Soper, George Grills, Yu-wei Cheng, Jianmin Huang, Hong Wang, Malgorzata A. Witek, Daniel Sang-won Park, Michael C. Murphy, Robin Lindsey McCarley, Mateusz L. Hupert
  • Nanoparticles, Nanosponges, Methods of Synthesis, and Methods of Use
    Publication number: 20170152439
    Abstract: Disclosed are novel metallic nanoparticles coated with a thin protective carbon shell, and three-dimensional nano-metallic sponges; methods of preparation of the nanoparticles; and uses for these novel materials, including wood preservation, strengthening of polymer and fiber/polymer building materials, and catalysis.
    Type: Application
    Filed: February 14, 2017
    Publication date: June 1, 2017
    Applicant: Board of Supervisors of Louisiana State University Agricultural and Mechanical College
    Inventor: Kun Lian
  • SYSTEMS AND METHODS FOR RECOGNIZING, CLASSIFYING, RECALLING AND ANALYZING INFORMATION UTILIZING SSM SEQUENCE MODELS
    Publication number: 20170154036
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Application
    Filed: January 9, 2015
    Publication date: June 1, 2017
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Method of making alkali metal hydrides
    Patent number: 9663364
    Abstract: A method is provided for making alkali metal hydrides by mechanochemically reacting alkali metal and hydrogen gas under mild temperature (e.g room temperature) and hydrogen pressure conditions without the need for catalyst, solvent, and intentional heating or cooling.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: May 30, 2017
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Vitalij K. Pecharsky, Shalabh Gupta, Marek Pruski, Ihor Hlova, Andra Castle
  • Methods and systems for monitoring patients undergoing treatment for cancer
    Patent number: 9662049
    Abstract: Oncology monitoring systems include: (a) a first plurality of radiation sensors configured to reside proximate a target tumor treatment site of a patient, the sensors being configured to provide radiation data associated with the tumor treatment site; and (b) a first portable receiver in communication with the plurality of sensors. The receiver is configured to obtain radiation data from the sensors at a plurality of different times. The receiver is in communication with a local and/or remote computer that tracks variation in the radiation data to provide dynamic tumor site information.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: May 30, 2017
    Assignees: North Carolina State University, SNC Holdings Corp.
    Inventors: Charles W. Scarantino, H. Troy Nagle, Lester C. Hall, Jeffrey Mueller, Bahram Ghaffarzadeh Kermani
  • SILICON-BASED POLYMER-DERIVED CERAMIC COMPOSITES COMPRISING H-BN NANOSHEETS
    Publication number: 20170144935
    Abstract: Polymer-derived ceramic composites are described herein. The composites are formed using hexagonal boron nitride nanosheet-functionalized silicon-based ceramic precursor polymers. The composites a matrix of a polymer-derived ceramic and hexagonal boron nitride nanosheets embedded therein. Silicon-derived ceramic precursors such as polysilazane and/or polysiloxane are used to create improved SiCN and/or SiOC ceramic composites.
    Type: Application
    Filed: July 8, 2015
    Publication date: May 25, 2017
    Applicant: Kansas State University Research Foundation
    Inventors: Gurpreet Singh, Lamuel David
  • ACETOLACTATE SYNTHASE HERBICIDE RESISTANT SORGHUM
    Publication number: 20170145436
    Abstract: The present invention provides for compositions and methods for producing sorghum crop plants that are resistant to herbicides. In particular, the present invention provides for sorghum plants, plant tissues and plant seeds that contain altered acetolactate synthase (ALS) genes and proteins that are resistant to inhibition by herbicides that normally inhibit the activity of the ALS protein.
    Type: Application
    Filed: January 26, 2017
    Publication date: May 25, 2017
    Applicant: Kansas State University Research Foundation
    Inventors: Mitchell R. Tuinstra, Kassim Al-Khatib
  • Baclofen solution for low-volume therapeutic delivery
    Patent number: 9655968
    Abstract: A high concentration baclofen solution is provided suitable for therapeutic use in a medical setting. A high concentration solution of baclofen in multivalent physiological ion solution such as artificial cerebrospinal fluid is provided with concentrations of baclofen of 10 mg/ml. Artificial cerebrospinal fluid is particularly advantageous as a baclofen solvent. A medical package is also provided for baclofen delivery to patients suffering from spasticity.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: May 23, 2017
    Assignee: Wayne State University
    Inventors: Jay M. Meythaler, Stephen M. Tuel
  • Assays for fungal infection
    Patent number: 9657355
    Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: May 23, 2017
    Assignee: Rutgers, the State University of New Jersey
    Inventors: Steven Park, David S. Perlin, David Wemyss Denning
  • Assays for resistance to echinocandin-class drugs
    Patent number: 9657334
    Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: May 23, 2017
    Assignees: Rutgers, The State University of New Jersey, Merck & Co., Inc.
    Inventors: David S. Perlin, Steven Park, Cameron M. Douglas, Jennifer N. Kahn, Stephen A. Parent, Rosemarie Kelly
  • Nano-electrode multi-well high-gain avalanche rushing photoconductor
    Patent number: 9660115
    Abstract: Provided is a detector that includes a scintillator, a common electrode, a pixel electrode, and a plurality of insulating layers, with a plurality of nano-pillars formed in the plurality of insulating layers, a nano-scale well structure between adjacent nano-pillars, with a-Se separating the adjacent nano-pillars, and a method for operation thereof.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: May 23, 2017
    Assignee: The Research Foundation for The State University of New York
    Inventors: Amirhossein Goldan, Wei Zhao, John A. Rowlands
  • Polymeric heart valve
    Patent number: 9655720
    Abstract: A polymeric valve which may include a heart valve, and also may include a trileaflet heart valve includes a stent having a base and a plurality of outwardly extending posts from the base and equidistant from each other. A plurality of leaflets each connected to a corresponding one of the posts at one end, and each of the leaflets connected to the base. Each of the leaflets having an operative end opposite the end connected to the post, and the operative ends of the leaflets being biased in a closed position such that the operative ends abut each other. The operative ends are configured to rhythmically open and close in relation to each other, and the leaflets include multiple cross sectional thicknesses at different portions of the leaflets.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: May 23, 2017
    Assignees: The Research Foundation for The State University of New York, The Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Danny Bluestein, Thomas E. Claiborne, Marvin J. Slepian
  • Method and apparatus for extracting and collecting single cells from formalin-fixed paraffin embedded tissues
    Patent number: 9658142
    Abstract: Methods and apparatuses are provided for extraction and collection of sets of one or more cells from a formalin-fixed paraffin embedded tissue sample. A laser is used to remove sets of one or more cells from an immobilized sample within a microfluidic device, and a fluid flow element washes the removed set of one or more cells away from the immobilized sample, preferably to be collected in a downstream sample collection device. Morphological and/or positional information may be preserved to permit at least one technique (e.g., amplification, sequencing, and/or analytical, optionally performed after cells are lysed downstream of the microfluidic device) to be related to the original spatial location of the set of one or more cells in the immobilized sample.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: May 23, 2017
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: David Richardson, Thai Tran, Dmitry Derkach, Colleen Ziegler
  • Formation and uses of europium complexes
    Patent number: 9655982
    Abstract: The present invention provides a method of forming an oxidatively-stable aqueous Eu(II) complex by synthesizing ligands that coordinate to large, soft, electron rich metals like Eu(II). The invention also provides an oxidatively stable aqueous Eu(II) complex. The complex can be used for a variety of purposes some of which include, but are not limited to, in paramagnetic chemical exchange saturation transfer, as a medical diagnostic, as a semiconductor, and for use in forming materials.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: May 23, 2017
    Assignee: Wayne State University
    Inventors: Matthew J. Allen, Nipuni Dhanesha H. Gamage, Joel Garcia, Jeremiah Moore
  • Recombinant non-animal cell for making biliverdin
    Patent number: 9657321
    Abstract: Methods for producing biliverdin in a microorganism, methods for producing biliverdin from a non-animal source, cells for producing biliverdin and methods for producing cells for producing biliverdin are disclosed.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: May 23, 2017
    Assignee: Utah State University
    Inventors: Jon Y. Takemoto, Dong Chen
  • Genetically engineered plants with increased vegetative oil content
    Patent number: 9657304
    Abstract: The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: May 23, 2017
    Assignee: Board of Trustees of Michigan State University
    Inventors: Christoph Benning, Sanjaya