Abstract: Biocompatible polyarylates of diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed.

Abstract: Methods for separating and purifying carbon nanomaterials such as trimetallic nitride endohedral metallofullerenes are described. In certain embodiments, carbon nanomaterials are contacted with a carbon nanomaterial reactive agent. The reactive agent binds empty cage fullerenes, nanotubes, and endohedral metallofullerenes without appreciably binding trimetallic nitride endohedral metallofullerenes. According to some embodiments, purified forms of trimetallic nitride endohedral metallofullerenes may be prepared.

Abstract: A method is provided for constructing a nanodevice. The method includes: fabricating an electrode on a substrate; forming a nanogap across the electrode; dispersing a plurality of nanoobjects onto the substrate using electrophoresis; and pushing one of the nanoobjects onto the electrode using a tip of an atomic force microscope, such that the nanoobject lies across the nanogap formed in the electrode. In addition, remaining nanoobjects may also be pushed away from the electrode using the atomic force microscope, thereby completing construction of a nanodevice.

Abstract: A one-step procedure for sentinel lymph node identification and biopsy using a single compound, a radiolabeled, low molecular weight dye (e.g., 125I-labeled methylene blue). This radiolabled dye is mixed with an unlabeled, similar molecular weight dye (e.g., isosulfan or methylene blue). The mixture is injected at the time of surgery, and rapidly migrates to reach the lymph nodes in less than 20 min, more preferably in less than 15 min and most preferably in less than 10 min. Using rabbits, rapid transit of 125I-methylene blue to regional lymph nodes with limited systemic biodistribution has been confirmed. By admixing small amounts of radiolabeled dye with a large amount of unlabeled dye, the sentinel lymph node identification was similar to that for the prior two-step dual mapping process, but with enhanced SLN localization because of the lower energy gamma emission of 125I as compared with 99mTc.

Abstract: A detectable complex and methods for use thereof are provided herein. The detectable complex includes: at least one target material; a first peptide tag bound to the at least one target material; and a second peptide tag bound to the at least one target material. The complex further includes a first conjugate having a detectable group and two pendant phenylarsine moieties comprising a first tag binding group; wherein the first conjugate preferentially associates with the first peptide tag; and a second conjugate having a detectable group and two pendant phenylarsine moieties comprising a second tag binding group; wherein the second conjugate preferentially associates with the second peptide tag. The mean distance and/or mean angle between the pendant phenylarsine moieties in the first conjugate is different from the mean distance and/or mean angle between the pendant phenylarsine moieties in the second conjugate.

Abstract: A deterministic shocker holds a test animal within an enclosure on a grid floor of electrodes such that a controller places a small current across each electrode and measures the electrical resistance of each electrode. The electrode with the lowest resistance strongly correlates to the location of a paw of the animal so that the controller delivers a small electric shock to only that electrode. Animal movement can be tracked and recorded during an experimental run. A second enclosure may be located adjacent the first enclosure separated by a transparent partition wherein the second enclosure also has a grid floor comprised of a plurality of electrodes, The controller also places a current across each of these electrodes and measures the electrical resistance thereof so that this animal's movement can also be tracked during the experiment to measure this second animal's response in witnessing the shocking of the first animal.

Abstract: Disclosed are major allergenic proteins in cashew nut, which are legumin-like proteins and 2S albumins. Also disclosed is a polypeptide allergen in the 7S superfamily, which includes vicilin-like and sucrose binding proteins. Several linear epitopes of the cashew nut are identified and characterized. The invention further discloses the sequence of cDNA encoding the allergenic polypeptide, the allergen being designated Ana o 1, and also describes the characterization of the expressed recombinant polypeptide and associated methods employing the polypeptide.

Abstract: The invention provides soybean plants having a novel determinant, Rps8, for resistance to Phytophthora sojae. The invention also provides methods for identifying germplasms that are either heterozygous or homozygous for Rps8 using marker assisted selection. Genetic and enzymatic markers with known chromosomal loci that are associated with the Rps8 locus are used to confirm Rps8-derived Phytophthora sojae resistance in germplasms. Marker assisted selection also used when introgressing Rps8-derived soybean Phytophthora sojae resistance into non-resistant soybean germplasm or less resistant soybean germplasms.

Abstract: A distal tip, and associated method of producing, of a biosensor ion sensing transducer for use in detecting an analyte comprising an halogenated organic compound in an environment such as soil or an aqueous environment. Features include: a biocomponent comprising at least one enzyme for carrying out a dehalogenation of the compound; the biocomponent is immobilized to a surface of the tip; a treatment of the biocomponent for maintaining a period of enzymatic efficacy; and the biocomponent stabilized by means preferably selected from the group consisting of crosslinking a surface of the immobilized biocomponent, crosslinking a polymer layer to the biocomponent, adding a gel-hardening agent to the biocomponent, adding a stabilizing agent to the biocomponent, and modifying a component of the immobilizing means. Immobilization can be carried out by: (a) entrapment within a hydrogel; (b) entrapment within a polymeric network; (c) (micro)encapsulation; (d) covalent-bonding; and (e) adsorption.

Abstract: Synthetic triple-helical peptides (THPs) are used for the design and synthesis of triple-helical transition state analog inhibitors. These inhibitors feature a phosphonate ester or phosphinic moiety in place of the scissle bond. These groups inhibit MMPs, and methods been developed for their convenient incorporation within a peptide sequence by solid-phase methods.

Abstract: Porphyrin compounds having a surface attachment group coupled thereto at the 5 position are described. The surface attachment group has the formula: wherein R is —CHCH2 or —CCH and Ar is an aromatic group. Methods and intermediates useful for making such compounds are also described.

Abstract: Methods have been developed for alleviating memory problems or psychiatric dysfunctions that have a memory formation component. These methods are based on the finding that a truncated form of an aPKC? protein is intimately involved in memory formation in animals. This finding is also central to methods for determining drugs that will have an effect on memory formation or the memory formation component of psychiatric dysfunctions.

Abstract: An underlying gallium nitride layer on a silicon carbide substrate is masked with a mask that includes an array of openings therein, and the underlying gallium nitride layer is etched through the array of openings to define posts in the underlying gallium nitride layer and trenches therebetween. The posts each include a sidewall and a top having the mask thereon. The sidewalls of the posts are laterally grown into the trenches to thereby form a gallium nitride semiconductor layer. During this lateral growth, the mask prevents nucleation and vertical growth from the tops of the posts. Accordingly, growth proceeds laterally into the trenches, suspended from the sidewalls of the posts. The sidewalls of the posts may be laterally grown into the trenches until the laterally grown sidewalls coalesce in the trenches to thereby form a gallium nitride semiconductor layer.

Abstract: Techniques for detecting optical spectral properties of a target are described. The technique includes providing an optical carrier which has an optical frequency bandwidth which is narrow compared to the width of the narrowest spectral feature of the target to be determined. This optical carrier is then electro-optically modulated with an RF frequency chirp, creating an optical chirp probe beam with a frequency chirped optical spectrum having upper and lower frequency chirped sidebands that have amplitudes sufficient to be detected at a detector. The sidebands are frequency bands arranged symmetrically around the optical carrier frequency. The attributes of a sideband include a start frequency, bandwidth and chirp rate. A probe beam is generated with the sidebands and directed onto a target having a physical property with optical frequency dependence. An optical response signal resulting from an interaction between the probe beam and the target is detected.

Abstract: Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein the transgene is expressed in the hen's oviduct and the transgene product is secreted in the hen's eggs and/or those of her offspring. In a preferred embodiment, the transgene product is secreted in the egg white.

Abstract: An improved routing scheme is provided for data packets in a network. Upon receiving incoming data packets at an intermediate routing node of the network, the incoming data packets are processed in accordance with a cross-layer protocol. In addition, network coding is applied to the incoming data packets to form a combined data packet which is in turn broadcast over the network.

Abstract: Composite materials with a polymer matrix, low resistivity graphite coated fillers having exfoliated and pulverized graphite platelets coated on an outer surface of high resistivity fillers, are provided. The fillers can be fibers or particles. The composite materials incorporating the graphite coated fillers as reinforcements can be electrostatically painted without using a conductive primer on the polymer matrix.

Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.

Abstract: Novel, simple methods are presented directed to the synthesis of nanofibers of polyaniline and substituted derivatives. The production of these fibers is achieved via various methods by controlling the concentration of aniline monomer or substituted aniline derivatives or an oxidant in the reaction medium and maintaining said concentration at a level much lower than conventional polyaniline synthesis methods. Methods are disclosed relating to the use of a permeable membrane to control the release of a monomer and/or oxidant as well as a bulk polymerization method.

Abstract: A new variety of sugarcane, identified as ‘L99-233’, is disclosed having superior sugarcane rust disease resistance, excellent ratooning ability, and high sugar/sucrose content and cane yield characteristics.