Patents Assigned to State University
  • HIGH SPEED, HIGH FIDELITY, HIGH SENSITIVITY NUCLEIC ACID DETECTION
    Publication number: 20120196771
    Abstract: Methods, compositions, and kits for nucleic acid detection.
    Type: Application
    Filed: November 17, 2011
    Publication date: August 2, 2012
    Applicant: ARIZONA BOARD OF REGENTS, A BODY CORPORATE ACTING FOR & ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Wayne Frasch, David Spetzler, Justin York
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR
    Publication number: 20120196325
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: April 9, 2012
    Publication date: August 2, 2012
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric R. Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • DETERMINING PHYSICAL PROPERTIES OF OBJECTS OR FLUIDS IN MULTI-PATH CLUTTER ENVIRONMENTS
    Publication number: 20120192617
    Abstract: A method for determining a physical property of an object or fluid in a dynamic multi-path clutter environment comprises transmitting an RF interrogation signal to a wireless sensor physically coupled to the object or fluid (gas or liquid) in the dynamic multi-path clutter environment, wherein the wireless sensor is operable to receive the RF interrogation signal, produce a reference signal and a measurement signal, and retransmit the reference signal and the measurement signal in the dynamic multi-path clutter environment. The reference signal and measurement signal are delayed by the wireless sensor by an amount of time that may be a function of the unknown physical property. The method also comprises receiving the retransmitted reference signal and the retransmitted measurement signal and comparing them in the time domain in order to determine the unknown physical property of the object or fluid.
    Type: Application
    Filed: August 3, 2011
    Publication date: August 2, 2012
    Applicants: SYNTONICS, LLC, THE OHIO STATE UNIVERSITY
    Inventors: Eric K. Walton, Yakup Bayram, Orbay Tuncay, Bruce G. Montgomery, Gary W. Bruce, Douglas E. Crowe, Steven E. Gemeny
  • High molecular weight polymers, devices and method for making and using same
    Patent number: 8232322
    Abstract: Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: July 31, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Anthony East, Alan Letton, Suseela Kanamathareddy, Bryant J. Pudil, Stephen Goodrich, Michael B. Hicks, Yun Choe
  • Procedure for preparing redox-active polymers on surfaces
    Patent number: 8231941
    Abstract: This invention provides novel methods for the formation of redox-active polymers attached to surfaces. In certain embodiments, the methods involve providing redox-active molecules bearing at least a first reactive site or group and a second reactive site or group; and contacting the surface with the redox-active molecules where the contacting is under conditions that result in attachment of said redox-active molecules to said surface via the first reactive site or group and attachment of redox-active molecules via the second reactive site or group, to the redox-active molecules attached to the surface thereby forming a polymer attached to said surface where the polymers comprise at least two of said redox-active molecules.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: July 31, 2012
    Assignees: The Regents of the University of California, The North Carolina State University
    Inventors: David F. Bocian, Zhiming Liu, Jonathan S. Lindsey
  • Benzimidazoles and pharmaceutical compositions thereof
    Patent number: 8232410
    Abstract: The present invention relates to novel benzimidazole derivatives and pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating a patient infected by Mycobacterium tuberculosis or Francisella tulerensis by administering to the patient a benzimidazole derivative or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: July 31, 2012
    Assignee: The Research Foundation of State University of New York
    Inventors: Iwao Ojima, Seung-yub Lee
  • High precision code plates and geophones
    Patent number: 8233154
    Abstract: An apparatus and method are disclosed for imaging a diffraction grating with a very high depth of focus, using a highly accurate code plate position measurement system. Positions may be measured to an accuracy of 1 nm or even smaller. The system may be used in fields such as manufacturing integrated circuits, and low- and very-low-frequency geophones, and other low- and very-low-frequency acoustic detectors.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: July 31, 2012
    Assignee: Board of Supervisors of Louisiana State University And Agricultural and Mechanical College
    Inventors: Martin Feldman, Li Jiang
  • Articles comprising a fibrous support
    Patent number: 8231013
    Abstract: Articles comprising a fibrous support of nanofibers and an interfacially polymerized polymer layer disposed on a surface of the fibrous support are useful, e.g., as fluid separation membranes.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: July 31, 2012
    Assignee: The Research Foundation of State University of New York
    Inventors: Benjamin Chu, Benjamin Hsiao, Kyunghwan Yoon
  • Method and device for manipulating liquids in microfluidic systems
    Patent number: 8231844
    Abstract: The present invention relates to microfluidic systems having components with specially designed and fabricated areas of enhanced and/or reduced capillarity (flow guides). The methods and devices of the present invention permit the bubble-less dispensing and mixing of small volumes of different liquids for subsequent incubation and/or detection of products of various biological reactions. Thus present invention is well-suited to applications such as polymerase chain reaction and capillary electrophoresis.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: July 31, 2012
    Assignee: The Research Foundation Of State University Of New York
    Inventors: Vera Gorfinkel, Evgeni A. Kabotyanski
  • Multi-state memory and multi-functional devices comprising magnetoplastic or magnetoelastic materials
    Patent number: 8233314
    Abstract: Apparatus and methods are disclosed that enable writing data on, and reading data of, multi-state elements having greater than two states. The elements may be made of magnetoplastic and/or magnetoelastic materials, including, for example, magnetic shape-memory alloy or other materials that couple magnetic and crystallographic states. The writing process is preferably conducted through the application of a magnetic field and/or a mechanical action. The reading process is preferably conducted through atomic-force microscopy, magnetic-force microscopy, spin-polarized electrons, magneto-optical Kerr effect, optical interferometry or other methods, or other methods/effects. The multifunctionality (crystallographic, magnetic, and shape states each representing a functionality) of the multi-state elements allows for simultaneous operations including read&write, sense&indicate, and sense&control.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: July 31, 2012
    Assignee: Boise State University
    Inventors: Peter Mullner, William B Knowlton
  • Reduction of flow-induced noise in a centrifugal blower
    Patent number: 8231331
    Abstract: A centrifugal blowing apparatus for reducing flow-induced noise is disclosed. The apparatus includes a blower housing having a scroll section formed about a rotational axis and an exhaust section extending from the scroll section. The scroll section includes an opening defining an inlet configured to draw in air and the exhaust section defines an outlet in fluid communication with the inlet. The scroll section commences with a reduced cross-sectional area defining a cutoff and expands to an increased cross-sectional area. An impeller is disposed in the opening of the scroll section about the rotational axis and includes an outer surface having impeller blades radially disposed thereon. The impeller blades rotate to direct a flow of air from the inlet through the scroll section to the outlet. A plurality of indentations is formed along an inner surface of the scroll section at the cutoff.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: July 31, 2012
    Assignee: Wayne State University
    Inventor: Sean F. Wu
  • Stereoregular ROMP polymers
    Patent number: 8232360
    Abstract: The invention relates to stereoregular ROMP polymers, the monomers used to make them, and the processes used to convert the monomers to the polymers.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: July 31, 2012
    Assignee: Research Foundation of State University of N.Y.
    Inventors: Nicole S. Sampson, Kathlyn A. Parker
  • 2,2-bis-(hydroxymethyl)cyclopropylidenemethyl-purines and -pyrimidines as antiviral agents
    Patent number: 8232275
    Abstract: Compounds which are active against viruses have the following formulas: wherein B is a purine or pyrimidine heterocyclic ring or base. In a preferred embodiment, the purine include 6-aminopurine (adenine), 6-hydroxypurine (hypoxanthine), 2-amino-6-hydroxypurine (guanine), 2,6-diamino-purine, 2-amino-6-azidopurine, 2-amino-6-halo substituted purines such as 2-amino-6-chloropurine, 2-amino-6-fluoropurine, 2-amino-6-alkoxypurines such as 2-amino-6-methoxypurine, 2-amino-6-cyclopropylaminopurine, 2-amino-6-alkylamino or 2-amino-6-dialkylamino substituted purines, 2-amino-6-thiopurine, 2-amino-6-alkylthio substituted purines, 3-deazapurines, 7-deazapurines and 8-azapurines. The pyrimidine incorporates cytosine, uracil and thymine, 5-halo substituted cytosines and uracils, 5-alkyl substituted cytosines and uracils including derivatives with a saturated or unsaturated alkyl group and 6-azapyrimidines.
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: July 31, 2012
    Assignees: Wayne State University, The Regents of the University of Michigan
    Inventors: Jiri Zemlicka, Shaoman Zhou, John C. Drach
  • Methods and systems for screening and treatment of young infants demonstrating deficits in auditory processing
    Patent number: 8231543
    Abstract: The present invention provides a method and apparatus for screening infants at high risk for central auditory processing deficits and then remediating less efficient processing behaviorally using an adaptive training algorithm that gradually increases sensitivity to rapidly occurring stimuli streams.
    Type: Grant
    Filed: October 13, 2007
    Date of Patent: July 31, 2012
    Assignee: Rutgers, The State University of New Jersey
    Inventors: April A. Benasich, Jason Nawyn, Cynthia P. Roesler, Teresa Realpe-Bonilla, Naseem Choudhury
  • ROBUST DIAPHRAGM FOR AN ACOUSTIC DEVICE
    Publication number: 20120189151
    Abstract: A rigid, flat plate diaphragm for an acoustic device is illustrated. The internal supporting structure of the diaphragm provides a combination of torsional and translational stiffeners, which resemble a number of crossbars. These stiffeners brace and support the diaphragm motion, thus causing its response to not be adversely affected by fabrication stresses and causing it to be very similar in dynamic response to an ideal flat plate operating in a frequency range that extends well beyond the audible.
    Type: Application
    Filed: January 25, 2011
    Publication date: July 26, 2012
    Applicant: Research Foundation of State University of New York
    Inventors: Ronald N. Miles, Weili Cui
  • MODULAR PRESSURE MANAGEMENT OIL SPILL CONTAINMENT SYSTEM AND METHOD
    Publication number: 20120186822
    Abstract: A modular pressure management oil spill containment system is constructed on the floor of an ocean to contain an oil spill caused by a wild well blowout. A base containment module including a hollow wall and at least one pressure relief valve is submerged below a surface of the ocean, positioned on a portion of the ocean floor that circumvents the wild well and its hollow wall is reinforced. At least one additional containment module including a hollow wall and at least one pressure relief valve is submerged below the ocean surface, positioned on top of the base containment module and its hollow wall is also reinforced. A plurality of riser assemblies are connected between at least a portion of the pressure relief valves of the containment modules and at least one containment vessel. The pressure relief valves are controlled to manage the containment of the oil spill.
    Type: Application
    Filed: January 20, 2011
    Publication date: July 26, 2012
    Applicants: Research Foundation of State University of New York, SUBSEA IP HOLDINGS LLC
    Inventors: Devinder Mahajan, Miriam Rafailovich, Scott Wolinsky
  • FLUOROGENIC COMPOUNDS CONVERTED TO FLUOROPHORES BY PHOTOCHEMICAL OR CHEMICAL MEANS AND THEIR USE IN BIOLOGICAL SYSTEMS
    Publication number: 20120190098
    Abstract: Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.
    Type: Application
    Filed: March 1, 2012
    Publication date: July 26, 2012
    Applicants: LELAND STANFORD JUNIOR UNIVERSITY, KENT STATE UNIVERSITY
    Inventors: ROBERT J. TWIEG, WILLIAM E. MOERNER, SAMUEL J. LORD, NA LIU, REICHEL SAMUEL
  • BEAM STEERING DEVICES INCLUDING STACKED LIQUID CRYSTAL POLARIZATION GRATINGS AND RELATED METHODS OF OPERATION
    Publication number: 20120188467
    Abstract: A beam steering apparatus includes a first beam steering stage and at least a second beam steering stage arranged in-line with the first beam steering stage. The first beam steering stage includes a first polarization grating comprising a uniaxial birefringent material having a first periodic director pattern, and the second beam steering stage includes a second polarization grating comprising a uniaxial birefringent material having a second periodic director pattern. In nonmechanical embodiments, a polarization selector may be arranged to provide a circularly polarized input beam incident on the first polarization grating. In mechanical embodiments, at least one of the first polarization grating and the second polarization grating may be operable to be independently rotated about an azimuth thereof. Related methods of operation are also discussed.
    Type: Application
    Filed: July 30, 2010
    Publication date: July 26, 2012
    Applicants: Boulder Nonlinear Systems, INc., NORTH CAROLINA STATE UNIVERSITY, a constituent in
    Inventors: Michael J. Escuti, Jihwan Kim, Chulwoo Oh, Steven Serati
  • MONOMERS AND PHASE-SEPARATED BIOCOMPATIBLE POLYMER COMPOSITIONS PREPARED THEREFROM FOR MEDICAL USES
    Publication number: 20120189713
    Abstract: The invention relates to novel monomers of Formula (I) useful for preparation of phase-separated biocompatible polymers or polymer compositions. These polymers or polymer compositions may be bioresorbable and/or biodegradable and have desirable mechanical properties, such as fracture and/or fatigue toughness, which have not been a primary design criteria for such polymers previously. The polymers or polymer compositions are useful in a variety of medical applications, such as in the fabrication of medical devices. Therefore, methods for preparing these polymers or polymer compositions and medical devices are also encompassed by this disclosure.
    Type: Application
    Filed: July 31, 2010
    Publication date: July 26, 2012
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Joachim B. Kohn, Durgadas Bolikal, Ramiro Rojas
  • SYSTEMATIC FRAMEWORK FOR APPLICATION PROTOCOL FIELD EXTRACTION
    Publication number: 20120191833
    Abstract: A computer-implemented system is provided for implementing application protocol field extraction. The system includes: an automata generator configured to receive the extraction specification that specifies data elements to be extracted from data packets and generate a counting automaton; and a field extractor configured to receive a data flow and operates to extract data elements from the data packets in accordance with the counting automaton. The extraction specification is expressed in terms of a context-free grammar, where the grammar defines grammatical structures of data packets transmitted in accordance with an application protocol and includes counters used to chronicle parsing history of production rules comprising the grammar.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 26, 2012
    Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Xiang-Yang A. Liu, Chad R. Meiners, Eric Torng