Patents Assigned to Steeno Research Group A/S
  • Synthetic IL-10 analogues
    Patent number: 6936586
    Abstract: The nonapeptide NH2-Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn-COOH (SEQ ID NO: 1) and related molecules are useful as IL-10 agonists.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: August 30, 2005
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Immunomodulators
    Patent number: 6599501
    Abstract: The nonapeptide Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn (SEQ ID NO:19) and certain related substances are useful as immunomodulators.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: July 29, 2003
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Antibodies that bind immunomodulators
    Patent number: 6168791
    Abstract: This invention relates to a polypeptide other than human interleukin (10) which has at least one of the following properties: a) induces inhibition of spontaneous IL-8 production by human monocytes, b) induces inhibition of IL-1 beta induced IL-8 production by human peripheral blood mononuclear cells (PBMC), c) induces production of interleukin-1 receptor antagonistic protein (IRAP) by human monocytes, d) induces chemotactic migration of CD8+ human T lymphocytes in vitro, e) desensitizes human CDS+ T cells resulting in an unresponsiveness towards rhIL-10,f) suppresses the chemotactic response of CD4+ T human lymphocytes towards IL-8, g) suppresses the chemotactic response of human monocytes towards MCAF/MCP-1, h) induces the production of IL-4 by cultured normal human CD4+ T cells, i) reduces the TNF alpha production in human mixed leukocyte reaction.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: January 2, 2001
    Assignee: Steeno Research Group A/S
    Inventors: Christian Grønhøj Larsen, Borbala Gesser
  • Immunomodulators
    Patent number: 6159937
    Abstract: The nonapeptide Ala-Tyr-Met-Thr-Met-Lys-Ile-Arg-Asn (SEQ ID NO:1) and certain related substances are useful as immunomodulators.
    Type: Grant
    Filed: January 6, 1997
    Date of Patent: December 12, 2000
    Assignee: Steeno Research Group A/S
    Inventors: Christian Gr.o slashed.nh.o slashed.j Larsen, Borbala Gesser