Patents Assigned to Stem Cell & Regenerative Medicine International, Inc.
  • METHOD OF GENERATING NATURAL KILLER CELLS AND DENDRITIC CELLS FROM HUMAN EMBRYONIC STEM CELL-DERIVED HEMANGIOBLASTS
    Publication number: 20150140657
    Abstract: This invention provides methods of generating natural killer (NK) cells and dendritic cells (DCs). The methods utilize human hemangioblasts as intermediate cells to generate the NK cells and DCs. In various embodiments, the methods do not require the use of stromal feeder layers.
    Type: Application
    Filed: August 21, 2014
    Publication date: May 21, 2015
    Applicant: Stem Cell & Regenerative Medicine International, Inc.
    Inventors: Erin Kimbrel, Shi-Jiang Lu
  • Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
    Patent number: 8822218
    Abstract: This invention provides methods of generating natural killer (NK) cells and dendritic cells (DCs). The methods utilize human hemangioblasts as intermediate cells to generate the NK cells and DCs. In various embodiments, the methods do not require the use of stromal feeder layers.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: September 2, 2014
    Assignee: Stem Cell & Regenerative Medicine International, Inc.
    Inventors: Erin Kimbrel, Shi-Jiang Lu
  • LARGE SCALE GENERATION OF FUNCTIONAL MEGAKARYOCYTES AND PLATELETS FROM HUMAN EMBRYONIC STEM CELLS UNDER STROMAL-FREE CONDITIONS
    Publication number: 20120315338
    Abstract: The present invention provides a method of generating megakaryocytes and platelets. In various embodiments, method involves the use of human embryonic stem cell derived hemangioblasts for differentiation into megakaryocytes and platelets under serum and stromal-free condition. In this system, hESCs are directed towards megakaryocytes through embryoid body formation and hemangioblast differentiation. Further provided is a method of treating a subject in need of platelet transfusion.
    Type: Application
    Filed: December 3, 2010
    Publication date: December 13, 2012
    Applicant: Stem Cell & Regenerative Medicine International, Inc.
    Inventors: Feng Li, Shi-Jiang Lu
  • METHOD OF GENERATING NATURAL KILLER CELLS AND DENDRITIC CELLS FROM HUMAN EMBRYONIC STEM CELL-DERIVED HEMANGIOBLASTS
    Publication number: 20120282693
    Abstract: This invention provides methods of generating natural killer (NK) cells and dendritic cells (DCs). The methods utilize human hemangioblasts as intermediate cells to generate the NK cells and DCs. In various embodiments, the methods do not require the use of stromal feeder layers.
    Type: Application
    Filed: December 1, 2010
    Publication date: November 8, 2012
    Applicant: Stem Cell & Regenerative Medicine International, Inc.
    Inventors: Erin Kimbrel, Shi-Jiang Lu