Abstract: A method of treating a patient with a neurodegenerative disease, such as ALS, using progenitor cells isolated from human umbilical cord blood. Non-invasive transplantation of aldehyde dehydrogenase (ALDH+) expressing progenitor cells provides cell replacement and protection of motor neurons.
Type:
Grant
Filed:
May 6, 2005
Date of Patent:
July 1, 2014
Assignees:
University of South Florida, Saneron CCEL Therapeutics, Inc., StemCo Biomedical, Inc.
Inventors:
Svitlana Garbuzova-Davis, Andrew Balber, Cyndy Davis-Sanberg, Tracy Gentry, Nicole Kuzmin-Nichols, Paul R Sanberg, Alison Willing