Patents Assigned to StemCyte, Inc.
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Publication number: 20220331370Abstract: This invention relates to cell-based treatment of cardiovascular disease. The invention also provides treatments to improve neural tissue and to improve behavior and neurological function in cardiovascular disease patients as well as patients suffering from other forms of neurological stress or damage.Type: ApplicationFiled: August 20, 2020Publication date: October 20, 2022Applicant: Stemcyte Inc.Inventors: Jonas Wang, Shinn Zong Lin, Horng-Jyh Harn, Po-Cheng Lin
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Publication number: 20220175674Abstract: This invention relates to processes and products for packaging and shipping therapeutic cells for cell therapy.Type: ApplicationFiled: May 12, 2020Publication date: June 9, 2022Applicants: Stemcyte Inc., Rutgers, The State University of New JerseyInventors: Monica Chen, Richard Tonai, Wise Young, Dongming Sun, Jonas Wang
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Patent number: 11318170Abstract: The invention relates to the treatment of chronic stroke, traumatic brain injury, and neurodegenerative disorders using umbilical cord blood cells.Type: GrantFiled: March 26, 2009Date of Patent: May 3, 2022Assignee: StemCyte, Inc.Inventors: Shinn-Zong Lin, Woei-Cherng Shyu, Hung Li
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Patent number: 10400212Abstract: This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.Type: GrantFiled: April 23, 2018Date of Patent: September 3, 2019Assignee: Stemcyte Inc.Inventors: Wise Young, Dongming Sun, Robert Fleischaker, Kam Sze Kent Tsang
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Publication number: 20180273901Abstract: This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.Type: ApplicationFiled: April 23, 2018Publication date: September 27, 2018Applicant: Stemcyte Inc.Inventors: Wise Young, Dongming Sun, Robert Fleischaker, Kam Sze Kent Tsang
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Patent number: 9951309Abstract: This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.Type: GrantFiled: February 14, 2012Date of Patent: April 24, 2018Assignee: Stemcyte Inc.Inventors: Wise Young, Dongming Sun, Robert Fleischaker, Kam Sze Kent Tsang
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Publication number: 20140227236Abstract: Disclosed are recombinant stem cells that are resistant to HIV infection. Also disclosed are their uses in treating AIDS.Type: ApplicationFiled: April 18, 2014Publication date: August 14, 2014Applicant: StemCyte, Inc.Inventor: Wise Young
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Publication number: 20140051165Abstract: This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.Type: ApplicationFiled: February 14, 2012Publication date: February 20, 2014Applicant: Stemcyte Inc.Inventors: Wise Young, Dongming Sun, Robert Fleischaker, Kam Sze Kent Tsang
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Publication number: 20120034197Abstract: Disclosed are recombinant stem cells that are resistant to HIV infection. Also disclosed are their uses in treating AIDS.Type: ApplicationFiled: April 6, 2010Publication date: February 9, 2012Applicant: STEMCYTE INC.Inventor: Wise Young
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Patent number: 8062837Abstract: The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and/or transplantation of hematopoietic stem cells to provide superior clinical outcome by maximizing post-processing cell recovery and post-thaw infusion cell dose. Methods for treating a wide variety of malignant diseases and benign diseases associated with the hematopoietic system by administering the UCB compositions of the present invention are also provided.Type: GrantFiled: June 2, 2006Date of Patent: November 22, 2011Assignee: StemCyte, Inc.Inventor: Robert Chow
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Patent number: 8048619Abstract: The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and/or transplantation of hematopoietic stem cells to provide superior clinical outcome by maximizing post-processing cell recovery and post-thaw infusion cell dose. Methods for treating a wide variety of malignant diseases and benign diseases associated with the hematopoietic system by administering the UCB compositions of the present invention are also provided.Type: GrantFiled: June 29, 2007Date of Patent: November 1, 2011Assignee: StemCyte, Inc.Inventor: Robert Chow
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Publication number: 20110256107Abstract: The invention relates to the treatment of chronic stroke, traumatic brain injury, and neurodegenerative disorders using umbilical cord blood cells.Type: ApplicationFiled: March 26, 2009Publication date: October 20, 2011Applicant: StemCyte, Inc.Inventors: Shinn-Zong Lin, Woei-Cherng Shyu, Hung Li
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Publication number: 20110172121Abstract: This invention provides methods for supplying a therapy for individuals exposed to radiation following a nuclear event, through the prospective establishment of an undesignated allogeneic stem cell bank with prospective HLA typing of healthy potential recipients.Type: ApplicationFiled: October 20, 2010Publication date: July 14, 2011Applicant: StemCyte, Inc.Inventors: Robert Chow, Lawrence D. Petz, Rubio R. Punzalan, Denis O. Rodgerson
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Publication number: 20100323920Abstract: This invention provides methods for supplying a therapy for individuals exposed to radiation following a nuclear event, through the prospective establishment of an undesignated allogeneic stem cell bank with prospective HLA typing of healthy potential recipients.Type: ApplicationFiled: April 16, 2010Publication date: December 23, 2010Applicant: StemCyte, Inc.Inventors: Robert Chow, Lawrence D. Petz, Rubio R. Punzalan, Denis O. Rodgerson
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Publication number: 20100310530Abstract: Disclosed are methods for conditioning stems cells and using the conditioned stems cells for treating brain tissue damage.Type: ApplicationFiled: May 21, 2010Publication date: December 9, 2010Applicant: StemCyte Inc.Inventors: Shinn-Zong Lin, Hung Li, Woei-Cherng Shyu, Hsiu-Mei Hsieh-Li
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Publication number: 20080227197Abstract: This invention provides methods for supplying a therapy for individuals exposed to radiation following a nuclear event, through the prospective establishment of an undesignated allogeneic stem cell bank with prospective HLA typing of healthy potential recipients.Type: ApplicationFiled: April 28, 2008Publication date: September 18, 2008Applicant: STEMCYTE, INC.Inventors: Robert Chow, Lawrence D. Petz, Rubio R. Punzalan, Denis O. Rodgerson
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Publication number: 20080166324Abstract: The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and/or transplantation of hematopoietic stem cells to provide superior clinical outcome by maximizing post-processing cell recovery and post-thaw infusion cell dose. Methods for treating a wide variety of malignant diseases and benign diseases associated with the hematopoietic system by administering the UCB compositions of the present invention are also provided.Type: ApplicationFiled: June 2, 2006Publication date: July 10, 2008Applicant: StemCyte, Inc.Inventor: Robert Chow
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Publication number: 20080008693Abstract: The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and/or transplantation of hematopoietic stem cells to provide superior clinical outcome by maximizing post-processing cell recovery and post-thaw infusion cell dose. Methods for treating a wide variety of malignant diseases and benign diseases associated with the hematopoietic system by administering the UCB compositions of the present invention are also provided.Type: ApplicationFiled: June 29, 2007Publication date: January 10, 2008Applicant: StemCyte, Inc.Inventor: Robert Chow
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Publication number: 20060275271Abstract: The umbilical cord blood (UCB) compositions of the present invention possess the unique features of having plasma that is substantially depleted from the UCB unit and red blood cells (RBC) that are not depleted from the UCB unit. Such UCB units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and/or transplantation of hematopoietic stem cells to provide superior clinical outcome by maximizing post-processing cell recovery and post-thaw infusion cell dose. Methods for treating a wide variety of malignant diseases and benign diseases associated with the hematopoietic system by administering the UCB compositions of the present invention are also provided.Type: ApplicationFiled: June 2, 2006Publication date: December 7, 2006Applicant: StemCyte, Inc.Inventor: Robert Chow
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Patent number: 6670124Abstract: A method for determining an HLA genotype of a subject is disclosed. The method comprises (a) isolating template nucleic acid from the subject; (b) amplifying the template nucleic acid to generate sufficient product for each allele of at least one gene locus to be determined; (c) hybridizing the template nucleic acid with an immobilized array of capture oligonucleotides, each having a known nucleic acid sequence of an HLA allele; and (d) determining the particular capture oligonucleotide to which the template nucleic acid hybridizes, thereby determining the genotype of the subject. A number of additional methods that can eliminate or abbreviate additional steps are also described. Moreover, the present invention provides a method for determining tissue compatibility using the determined HLA genotype.Type: GrantFiled: December 20, 2000Date of Patent: December 30, 2003Assignee: StemCyte, Inc.Inventors: Robert Chow, Richard Tonai