Abstract: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.
Type:
Application
Filed:
February 17, 2012
Publication date:
June 13, 2013
Applicant:
STEMDER INC.
Inventors:
Myung Kwan Han, Chae Hwa Yoo, Eun Kyung Song, Seung Ok Lee