Abstract: The present invention provides proteins/genes, which are essential for survival, and consequently, for virulence of Streptococcus pneumoniae in vivo, and thus are ideal vaccine candidates for a vaccine preparation against pneumococcal infection. Further, also antibodies against said protein(s) are included in the invention.
Type:
Application
Filed:
October 7, 2009
Publication date:
December 15, 2011
Applicant:
STICHTING KATHOLIEKE UNIVERSITEIT, MORE PARTICULARLY THE RADBOUD UNIVERISTY NIJMEGEN MEDIC
Inventors:
Peter Wilhelmus Maria Hermans, Hester Jeanette Bootsma, Pieter Jan Burghout, Christian Ostergaard Andersen, Oscar Paul Kuipers, Johanna Jacoba Elisabeth Bijlsma, Thomas Gerrit Kloosterman