Patents Assigned to STICHTING MAASTRICHT RADIATION ONCOLOGY "MAASTRO-CLINIC"
  • Endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject
    Patent number: 12029917
    Abstract: The invention relates to the radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. In particular the invention relates to an endorectal probe device for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject. Furthermore the invention relates to an afterloading apparatus for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject using an endorectal probe device according to the invention. Moreover the invention relates to a method for effecting radiation treatment of colorectal cancerous tissue in the rectum of a human or animal subject, wherein the method implements the endorectal probe device according to the invention.
    Type: Grant
    Filed: October 17, 2022
    Date of Patent: July 9, 2024
    Assignees: UNIVERSITEIT MAASTRICHT, STICHTING MAASTRICHT RADIATION ONCOLOGY MAASTRO CLINIC, ACADEMISCH ZIEKENHUIS MAASTRICHT
    Inventors: Frank Verhaegen, Murillo Bellezzo, Evert Van Limbergen, Maaike Berbee, Brigitte Reniers, Gabriel Paiva Fonseca
  • Device for supporting the testing of a brachytherapy applicator and a method for testing of such a brachytherapy applicator prior to the use of the brachytherapy applicator in brachytherapy radiation treatments
    Patent number: 11487028
    Abstract: The invention relates to a device for supporting the testing of a brachytherapy applicator prior to the use of the brachytherapy applicator in brachytherapy radiation treatments. The invention also relates to a method for testing of a brachytherapy applicator prior to the use of the brachytherapy applicator in brachytherapy radiation treatments.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: November 1, 2022
    Assignees: UNIVERSITET MAASTRICHT, STICHTING MAASTRICHT RADIATION ONCOLOGY “MAASTRO-CLINIC”, ACADEMISCH ZIEKENHUIS MAASTRICHT
    Inventors: Frank Verhaegen, Gabriel Paiva Fonseca, Robert Voncken
  • Method and system for determining a phenotype of a neoplasm in a human or animal body
    Patent number: 9811904
    Abstract: The present invention relates to a decision support system and an image analysis method for providing information for enabling determination of a phenotype of a neoplasm in a human or animal body for enabling prognostication, comprising the steps of: receiving, by a processing unit, image data of the neoplasm; and deriving, by the processing unit, a plurality of image feature parameter values from the image data, said image parameter values relating to image features associated with the neoplasm; and deriving, by said processing unit using a signature model, one or more neoplasm signature model values associated with the neoplasm from said image feature parameter values, wherein said signature model includes a functional relation between or characteristic values of said image feature parameter values for deriving said neoplasm signature model values.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: November 7, 2017
    Assignee: STICHTING MAASTRICHT RADIATION ONCOLOGY “MAASTRO-CLINIC”
    Inventors: Philippe Lambin, Hugo Johannes Wilhelmus Louis Aerts
  • CANCER TARGETING USING CARBONIC ANHYDRASE ISOFORM IX INHIBITORS
    Publication number: 20150150849
    Abstract: The present invention concerns novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety and their use in therapy of hypoxic conditions, in particular cancer treatment, especially chemotherapy and radiotherapy. The compounds of the invention have an increased specificity for the carbonic anhydrase IX enzyme compared to the art.
    Type: Application
    Filed: February 4, 2015
    Publication date: June 4, 2015
    Applicants: STICHTING MAASTRICHT RADIATION ONCOLOGY "MAASTRO- CLINIC", UNIVERSITE MONTPELLIER 2 Sciences et Techniques
    Inventors: Philippe Lambin, Jean-Yves Winum, Claudiu Supuran
  • CANCER TARGETING USING CARBONIC ANHYDRASE ISOFORM IX INHIBITORS
    Publication number: 20130274305
    Abstract: The present invention concerns novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety and their use in therapy of hypoxic conditions, in particular cancer treatment, especially chemotherapy and radiotherapy. The compounds of the invention have an increased specificity for the carbonic anhydrase IX enzyme compared to the art. The present invention relates to novel nitroimidazole derivates represented by formula (1).
    Type: Application
    Filed: December 21, 2011
    Publication date: October 17, 2013
    Applicants: STICHTING MAASTRICHT RADIATION ONCOLOGY "MAASTRO-CLINIC", CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Philippe Lambin, Jean-Yves Winum, Claudiu Supuran