Patents Assigned to STIFTUNG CAESAR
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Patent number: 9801539Abstract: The present invention relates to an Ocular Videography System for tracking eye movements of an animal, in particular rats, comprising a camera system suitable of being positioned on the head of an animal to track eye movements of at least one eye of the animal, a head mount on which the camera system is fixed or fixable, wherein, at least one image sensor as well as at least one decoder, for decoding a signal detected by the image sensor, each being comprised by the camera system, and wherein the camera system, and in particular a camera of the camera system, is designed in such a way that it detects a movement of the eye and/or a movement of the head of the animal in a vertical and/or horizontal and/or a torsional direction to an optical axis of the camera system and/or of the optical axis of the animal's eye without interfering with the animal's natural motion dynamics.Type: GrantFiled: May 23, 2014Date of Patent: October 31, 2017Assignee: STIFTUNG CAESAR—CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCHInventors: Jason Kerr, Damian Haydon Wallace, Juergen Sawinski, David Greenberg
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Publication number: 20150077543Abstract: The present invention relates to an Ocular Videography System for tracking eye movements of an animal, in particular rats, comprising a camera system suitable of being positioned on the head of an animal to track eye movements of at least one eye of the animal, a head mount on which the camera system is fixed or fixable, wherein, at least one image sensor as well as at least one decoder, for decoding a signal detected by the image sensor, each being comprised by the camera system, and wherein the camera system, and in particular a camera of the camera system, is designed in such a way that it detects a movement of the eye and/or a movement of the head of the animal in a vertical and/or horizontal and/or a torsional direction to an optical axis of the camera system and/or of the optical axis of the animal's eye without interfering with the animal's natural motion dynamics.Type: ApplicationFiled: May 23, 2014Publication date: March 19, 2015Applicant: Stiftung Caesar - Center of Advanced European Studies and ResearchInventors: Jason KERR, Damian Haydon WALLACE, Juergen SAWINSKI, David GREENBERG
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Publication number: 20100104641Abstract: The invention relates to a therapeutic composition, a method for producing a therapeutic composition, and the use of a cell-free substance, especially a cell-free bone or cartilage matrix. The disclosed therapeutic composition comprises at least a cell-free substance obtained from stimulated stem cells and/or precursor cells. Immunogenic reactions during in vivo therapeutic use are prevented by the fact that the therapeutic composition is free from cells and contains no typically antigenic cell components. The disclosed composition can therefore be universally used for the therapeutic purposes regardless of the origin of the stem cells and/or precursor cells and utilize the natural regenerative potency thereof in a highly efficient manner for replacing tissue, e.g. for a suitable bone and/or cartilage structure.Type: ApplicationFiled: February 1, 2008Publication date: April 29, 2010Applicant: STIFTUNG CAESARInventors: Michael Thie, Oezer Degistirici
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Publication number: 20090324555Abstract: Subject of the invention is a method for generating neural stem cells in vitro, wherein dental progenitor cells are isolated from soft tissue of tooth or wisdom tooth and cultivated until they form primary spheres which are then dissociated into single cells. These single cells are cultivated until they form spheroids and the spheroid-forming cells are separated to obtain neural stem cells.Type: ApplicationFiled: March 23, 2006Publication date: December 31, 2009Applicant: STIFTUNG CAESARInventors: Michael Thie, Özer Degistirici
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Publication number: 20090022693Abstract: The invention relates to a method for isolation of multipotent stem cells from dental tissue in which the stem cells are extracted from a tissue structure and then cultured. The invention also relates to stem cells isolated by means of the method according to the invention as well as bone cells and nerve cells produced by means of the method according to the invention. The invention also relates to a method for producing a bank of stem cells in which the cells are stored by means of the method according to the invention. According to the present invention, the cells of a pad-like soft tissue that can be localized beneath the papilla directly on the apical side of an extracted immature tooth are cryopreserved in the tissue structure such that the tissue structure is disintegrated to extract the stem cells only after thawing.Type: ApplicationFiled: July 17, 2006Publication date: January 22, 2009Applicant: STIFTUNG CAESARInventors: Michael Thie, Ozer Degistirici
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Patent number: 7019830Abstract: A process for qualitative and quantitative analysis of an analyte in a solution includes irradiating a first chromophore with an electro-magnetic radiation while simultaneously moving an arrangement structure and the analyte relative to one another in a manner which effects extension of the elastic coupling interconnecting the first chromophore and a second chromophore. The process also includes measuring the intensities of a fluorescent light having a respective wavelength ?1 and a fluorescent light having a respective wavelength ?2 during the movement of the arrangement structure and the analyte relative to one another. The type and the amount of the analyte is determined as a function of the intensities of the fluorescent light having the respective wavelength ?1 and the fluorescent light having the respective wavelength ?2.Type: GrantFiled: May 15, 2003Date of Patent: March 28, 2006Assignee: Stiftung Caesar Ctr-Advanced European Studies & ResearchInventors: Daniel Hoffman, Michael Moske
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Patent number: 6988414Abstract: A sensor device having a magnetostrictive force sensor is provided. To detect a force, the sensor device contains a TMR force sensor element having a magnetic detection layer of material having a magnetostriction coefficient ??|5·10?6|, a magnetically harder reference layer, and a tunnel barrier disposed between these layers. Established in the detection layer is a starting magnetization that relative to the magnetization of the reference layer, which is directed in the direction of force, forms an angle of other than 0° and thus is rotated out of its starting position under the effect of the force.Type: GrantFiled: April 29, 2004Date of Patent: January 24, 2006Assignees: Stiftung Caesar Center of Advanced European Studies and Research, Infineon Technologies AGInventors: Manfred Rührig, Joachim Wecker, Alfred Ludwig, Eckhardt Quandt, Markus Löhndorf