Abstract: A device for heating infusion and transfusion solutions includes an automatically temperature controlled, electrically heated heat exchange unit having an exposed cylindrical outer surface provided with a helical groove removably receiving and holding with a clamping effect a flexible infusion tube through which the solution to be heated flows. A sleeve of thermal insulation material having its inner surface covered with an aluminum foil closely surrounds the outer surface of the unit and the tube seated in the groove. Safety clamps secured to casing portions at opposite ends of the heat exchange unit insure that the tube is held in the groove.