Patents Assigned to Stitching Rega VZW
  • N3-alkyl-2',5'-0-silylated-3'-spiro-thymidine derivatives
    Patent number: 5527900
    Abstract: Nucleoside analogs possessing anti-HIV activity and having a 3'-spiro moiety and blocking groups at the 2'- and 5'-positions. The preferred species is shown in the structure below: ##STR1## wherein R is alkyl.
    Type: Grant
    Filed: September 3, 1992
    Date of Patent: June 18, 1996
    Assignees: Stitching Rega VZW, Consejo Superior de Investigaciones Instituto de Quimica Medica
    Inventors: Jan M. R. Balzarini, Erik D. A. De Clerco, Maria-Jose Camarasa-Rius, Maria J. Perez-Perez, Ana San-Felix-Garcia