Patents Assigned to Stolle Milk Biologics, Inc.
  • Patent number: 10478493
    Abstract: The invention relates to a method for treating protozoal gastrointestinal disorders in immunocompromised patients. It includes a method for the isolation of a factor from the milk of hyperimmunized animals in a substantially pure form, and to the use of said factor in combination with vitamins and minerals.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: November 19, 2019
    Assignee: Stolle Milk Biologics, Inc.
    Inventors: Joseph Whelihan, Jada Eley
  • Patent number: 6056978
    Abstract: The invention relates to the use of hyperimmune milk derived from milk producing animals hyperimmunized with bacterial antigens including intestinal bacteria. The present hyperimmune milk effectively prevents the decline of immunological functions observed in aging or immunocompromised animals and prevents the translocation of indigenous enteric bacteria from the GI tract of immunocompromised or aged animals, thereby preventing indigenous infection. More specifically, the present hyperimmune milk is administered to an animal in an amount sufficient to effectively prevent translocation of indigenous enteric bacteria in, delay the onset of, lower the rate of, or restore the declining immune functions of, aging or otherwise immunocompromised animals.
    Type: Grant
    Filed: April 10, 1995
    Date of Patent: May 2, 2000
    Assignee: Stolle Milk Biologics, Inc.
    Inventors: Lee R. Beck, Atsunori Ishida, Yasunobu Yoshikai, Shinji Murosaki, Chiharu Kubo, Yoshio Hidaka, Kikuo Nomoto
  • Patent number: 6054124
    Abstract: An immune suppressive product prepared by injecting an allergen or a mixture of allergens into the body of milk-producing species. Said product being the milk or a polypeptide subfraction of milk obtained from the allergen treated host. The immune suppressive product(s) is milk and or the polypeptide fractions contained therein, which is ostensively free of the intact allergen or allergens used for the treatment of the host. The immune suppressive factor(s) being a subfraction of the allergen used for the treatment. A method of preparing immune suppressive polypeptides from intact allergens, which involves injection of the specific intact allergens into a milk-producing species, collecting the immune suppressive polypeptide fractions of the intact allergens from the milk of the treated host. The immune suppressive milk containing said polypeptide fractions, and/or the polypeptide fractions obtained from said milk, are nonreactive in animals and humans as allergens.
    Type: Grant
    Filed: December 30, 1991
    Date of Patent: April 25, 2000
    Assignee: Stolle Milk Biologics, Inc.
    Inventors: Lee R. Beck, Ralph J. Stolle
  • Patent number: 5980953
    Abstract: The invention relates to an anti-inflammatory factor isolated from milk, methods of purifying the anti-inflammatory factor resulting in substantially or highly purified preparations and to methods for using this factor to remove adhered neutrophils from endothelial cells, to prevent the emigration of cells from the vasculature and to suppress the response of lymphocytes to foreign antigens.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: November 9, 1999
    Assignee: Stolle Milk Biologics, Inc.
    Inventors: Lee R. Beck, J. Peter Fuhrer