Patents Assigned to STONY BROOK UNIVERSITY
  • INHIBITION OF BRAIN ENZYMES INVOLVED IN CEREBRAL AMYLOID ANGIOPATHY AND MACULAR DEGENERATION
    Publication number: 20100047336
    Abstract: A method of treating or inhibiting progress of dementia and/or macular degeneration in a mammal involves administering compositions containing siRNA to heme oxygenase-1 (HO-1) or heme oxygenase-2 (HO-2), a matrix metalloproteinase (MMP) inhibitor, a caspase inhibitor, or a metalloporphyrin in a manner that permits access to brain sites and/or the macula of the patient.
    Type: Application
    Filed: August 17, 2009
    Publication date: February 25, 2010
    Applicants: LOMA LINDA UNIVERSITY MEDICAL CENTER, GEORGE MASON UNIVERSITY, STONY BROOK UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Wolff Kirsch, Lance A. Liotta, William Van Nostrand, Harry V. Vinters, Virginia A. Espina
  • INHIBITION OF BRAIN ENZYMES INVOLVED IN CEREBRAL AMYLOID ANGIOPATHY AND MACULAR DEGENERATION
    Publication number: 20090018094
    Abstract: A method of treating or inhibiting progress of dementia and/or macular degeneration in a mammal involves administering compositions containing siRNA to heme oxygenase-1 (HO-1) or heme oxygenase-2 (HO-2), a matrix metalloproteinase (MMP) inhibitor, a caspase inhibitor, or a metalloporphyrin in a manner that permits access to brain sites and/or the macula of the patient.
    Type: Application
    Filed: November 30, 2007
    Publication date: January 15, 2009
    Applicants: LOMA LINDA UNIVERSITY MEDICAL CENTER, GEORGE MASON UNIVERSITY, STONY BROOK UNIVERSITY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Wolff Kirsch, Lance A. Liotta, William Van Nostrand, Harry V. Vinters, Virginia A. Espina