Abstract: Provided is a binding protein that binds CD40 and is an agonist thereof. In a particular embodiment the invention provides an agonistic anti-CD40 antibody. Also provided are bispecific conjugates comprising the binding protein, and complexes comprising the bispecific conjugates non-covalently bound to a tag construct comprising an antigen, for antigen delivery to immune cells. Medical uses of the binding proteins, conjugates and complexes of the invention are also provided.
Type:
Grant
Filed:
May 28, 2021
Date of Patent:
May 19, 2026
Assignee:
STRIKE PHARMA AB
Inventors:
Sara Mangsbo, Helena Persson Lotsholm, Oskar Andersson