Abstract: Compounds of formula R1-A-NH—CH(R2)—CO—R3 are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.
Type:
Grant
Filed:
April 21, 2014
Date of Patent:
October 27, 2015
Assignee:
STRONGBONE AB
Inventors:
Anders Grubb, Franciszek Kasprzykowski, Ulf Lerner, Beata Zolnowska, Regina Kasprzykowska
Abstract: Compounds of formula R1-A-NH—CH(R2)—CO—R3 are presented. The compounds can be used to treat or alleviate conditions associated with bone loss or low bone density, or to inhibit osteoclast differentiation and stimulation, bone resorption and/or loosening of a prosthetic device. The compounds can be administered as a pharmaceutical composition or in a prosthetic device.
Type:
Application
Filed:
April 21, 2014
Publication date:
August 28, 2014
Applicant:
Strongbone AB
Inventors:
Anders GRUBB, Franciszek KASPRZYKOWSKI, Ulf LERNER, Beata ZOLNOWSKA, Regina KASPRZYKOWSKA
Abstract: Novel compounds which may be for treatment, prevention or alleviation of a condition associated with bone loss or low bone density or to inhibit osteoclast differentiation and stimulation, bone resorption, or loosening of a prosthetic device.
Type:
Grant
Filed:
June 17, 2010
Date of Patent:
June 10, 2014
Assignee:
Strongbone AB
Inventors:
Anders Grubb, Franciszek Kasprzykowski, Ulf Lerner, Beata Zolnowska, Regina Kasprzykowska