Abstract: A flexible bag for protecting luggage includes first and second opposing panel sections joined by a gusset at a first end. The first and second panel sections are secured together along first and second opposite edges with the gusset therebetween, to form a containment region between the first and second panel sections and bordered by the first and second edges and the gusset. A mouth is defined by the first and second panel sections at a second end opposite to the first end. The mouth is movable from an open position to a closed position, and provides access to the containment region when in the open position. A tamper-evident closure arrangement is at the mouth for securing the mouth in the closed position. The closure arrangement includes an adhesive region held by the second panel section, and a flap arrangement integral to the first panel section.