Abstract: A device for providing reference information in laser speckle medical imaging of tissue of a subject can include a support that includes a marker for image recognition and a speckle target region that is nontransparent to light in a first illumination wavelength range and that generates a speckle pattern when illuminated with light in the first wavelength range. The support can be configured to be attachable to tissue of the subject.

Abstract: A computer-implemented method for guiding a surgeon to acquire one or more registration points on a body of a patient. The method includes matching a non-patient-specific virtual mask to image data of a patient, and obtaining a plurality of image surface points defining a skin surface in the image data. The method further comprises determining, based on the matched virtual mask, for at least one of the plurality of image surface points, a priority value indicative of a priority for acquiring a registration point at a position, relative to the patient's body, that corresponds to a position of the at least one image surface point relative to the skin surface defined in the image data. The method also includes triggering display of a visualization of the priority value, or of a visualization of information derived from the priority value.

Abstract: An expandable implant for bone restoration. The implant includes a first end element and a second end element. A plate is expandable in a first direction, and a blade expandable in a second direction. A first interconnecting element extends between the plate and at least one of the first and second end elements. A second interconnecting element extends between the blade and at least one of the first and second end elements. When the implant is in a collapsed position, a length of the blade is substantially parallel to the longitudinal axis, and when the blade is in an expanded position, the length of the blade is non-parallel to the longitudinal axis. The blade may include a length extending from a base to a tip, and the tip of the blade is further from the longitudinal axis than the plate when the implant is in the expanded position.

Abstract: A flat embolic braid having a first side comprising a first side surface, and a second side comprising a second side surface facing in an opposite direction than the first side surface, the braid having an elongated constrained configuration for being deployed through a delivery catheter, and a three-dimensional unconstrained configuration, wherein in the three-dimensional unconstrained configuration, the braid assumes a plurality of successive loops in which the braid is at least partially twisted between successive loops of the plurality, so that the first side surface faces externally of each loop, and the second side surface faces an interior of each loop, respectively, regardless of a change in direction and/or orientation of the braid.

Abstract: An embolic device for placement in a body lumen, includes: an elongated member having a linear configuration when in room temperature, the elongated member being configured to form a first three-dimensional structure in response to body temperature; wherein the elongated member comprises a first segment, a second segment, and a third segment, the second segment being located between the first segment and the third segment; wherein the first segment and the third segment are configured to change their respective shapes in response to the body temperature; and wherein the second segment that is located between the first segment and the third segment has a shape that is independent of the body temperature.

Abstract: A method for guiding a surgeon on how to adapt a pre-planned position of an implant interface. The implant interface is configured to couple to an implant connector configured to connect the implant interface with an implant interface of another implant. The method is performed by a processing system and comprises obtaining a pre-planned position of an implant interface, obtaining reference positions of the implant interface, determining a deviation between the pre-planned position and the reference positions, and triggering display of a visualization comprising an indication of the deviation to guide a surgeon on how to adapt the pre-planned position of the implant interface. A system and a computer program are also described.

Abstract: A method for visualizing a planned implant. The method includes obtaining image data representative of an anatomical element, obtaining implant data indicative of geometrical properties of an implant to be implanted into the anatomical element, and obtaining planning data indicative of a planned pose of the implant. Based on the obtained data, a first part of the implant that lies inside the anatomical element, and a second part of the implant that does not lie inside the at least one anatomical element are determined. A display of a visualization indicating the first part distinguishably from the second part is triggered. The disclosure also relates to a system and a computer program.

Abstract: An intravascular device includes an elongated body having a proximal end and a distal end, and a plurality of energy transmitting conduits extending within the elongated body. The distal ends of the energy transmitting conduits terminate at different axial locations along the distal end of the elongated body. In one embodiment, the number of energy transmission conduits is only two, such that the number of bends in the compound curve assumed by the distal end of the elongated body is only two, although the number of energy transmission conduits may be any suitable number.

Abstract: Methods and systems for facilitating assessment of blood flow in a tissue volume of a subject are disclosed. In some variations, the method may include: after a predetermined amount of a fluorescence agent has been administered to the subject, exciting the fluorescence agent in the tissue volume such that the excited fluorescence agent emits fluorescent light, acquiring fluorescence data based on the fluorescent light emitted during blood flow through the tissue volume, estimating a molar concentration of the fluorescence agent in the blood flowing through the tissue volume, and generating an assessment of blood flow in the tissue volume based at least in part on the fluorescence data and the estimated molar concentration of the fluorescence agent. The estimated molar concentration may be based on the predetermined amount of the fluorescence agent and an estimated circulating blood volume of the subject.

Abstract: A method, a system, and a computer program for determining a visualization of content to be displayed to a surgeon on a display of a portable display device are provided. First pose data indicative a first pose of an anatomical feature of a patient in an operating room and second pose data indicative of a second pose of a portable display device in the operating room are obtained. Based on the first pose data and the second pose data, a third pose of a surgeon relative to the patient is estimated. Based on the estimated third pose, a visualization of content to be displayed to the surgeon on a display of the portable display device is determined.

Abstract: Methods and systems for alignment of a subject for medical imaging are disclosed, and involve capturing an image of an anatomical region comprising a target tissue and determining, based on the image and based on a reference image, that a current alignment of the image capture device is aligned with a predefined alignment. The determination is performed before initiating capturing of a time series of fluorescence medical images from fluorescence emission. In response to the determining that the current alignment is aligned with the predefined alignment, capturing of the time series of fluorescence medical images from the fluorescence emission is initiated.

Abstract: A method for securing a fractured bone includes inserting an intramedullary nail into an intramedullary canal of the bone; driving a bone screw into the bone such that a head of the bone screw is anchored in a cortical region of the bone; installing a bone plate against the bone to cover the head of the bone screw with an inner surface of the bone plate; and driving a plate screw through a plate hole of the bone plate into the underlying bone.

Abstract: A catheter includes: a tubular structure having a longitudinal axis; wherein the tubular structure comprises first and second rings arranged in series along the longitudinal axis, the first and second rings being respective closed-loops, wherein the first ring lies within a first plane that is substantially perpendicular to the longitudinal axis; wherein the tubular structure comprises a first connecting member having a first end, a second end, and a member body; and a second connecting member comprises a first end, a second end, and a member body; and wherein the second end of the first connecting member and the first end of the second connecting member are connected to the first ring, and disposed across from each other, and wherein the second end of the second connective member is connected to the second ring, and wherein the respective member bodies are configured to rotate and/or bent.

Abstract: A vaso-occlusive coil formed of a wire having a primary configuration in a constrained condition. The coil assumes a secondary configuration in a relaxed, unconstrained condition. The secondary configuration comprises a primary portion comprising a plurality of primary loops, including a distal-most primary loop. A distal anchoring loop is connected to the distal end of the distal-most primary loop. The distal anchoring loop has a substantially triangular shape and is much smaller than the distal-most primary loop. The distal anchoring loop prevents herniation of the device during deployment and retention within an anatomical cavity.

Abstract: An intravascular device comprises an elongated outer catheter body having a proximal catheter end, a distal catheter end, and an inner catheter lumen extending between the proximal catheter end and the distal catheter end. The intravascular device further comprises an elongated inner articulating member slidably disposed within the inner catheter lumen. The inner articulating member has a proximal member end and an articulatable distal member end. The intravascular device further comprises a control assembly mechanically coupled to the proximal catheter end and the proximal member end. The control assembly is configured for distally translating the outer catheter body over the inner articulating member, and for articulating the distal member end.

Abstract: In one embodiment, the present disclosure relates to a probe for use in minimally invasive surgery. The probe includes a shaft and a tip extending from the shaft. The tip includes a bulbous shape with a smooth and rounded outer surface. In some embodiments, the shaft is separated from the tip by a neck such that both the shaft and the tip expand outward from a concave surface of the neck. In some embodiments, one or both of a neuromonitoring element and an ultrasound sensor are disposed on the tip. In some embodiments, a probe may include a surface feature that resists expulsion of the probe from a human body when the probe is disposed in the human body. In further embodiments, a probe may include insulated material over a first surface region and conductive material over a second surface region.

Abstract: A method of displaying a colorized luma image includes illuminating tissue under observation with illumination light and excitation light. A color image from reflectance of the illumination light and a fluorescence image produced by illuminating the tissue under observation with the excitation light are simultaneously detected at an image sensor to produce image data comprising both color image data and fluorescence image data. A luma image from the detected color image data is computed and the luma image is colorized based on the detected fluorescence image data. The colorized luma image is then displayed.

Abstract: A system configured to increase height of a vertebral body. An implant includes plates each defining a bearing surface configured to be moved away from one another to expand the implant within the vertebral body. Supports are each coupled to one of the plates and include a reduced thickness portion defining a material web configured to plastically deform during expansion of the implant. The system includes an implant carrier with which an end element of the implant is removably coupled, and a rod configured to be translated relative to the implant carrier to cause expansion of the implant. An opposed portion may be coupled to the supports and configured to receive a longitudinal force to be moved relative to the end element. Second supports may be each coupled to the end element and one of the plates. Each of the second supports may plastically deform during expansion of the implant.