Abstract: A surgical tool system (20) with replaceable surgical cutting accessories (26) and attachments (34) for holding the tools. This system includes a handpiece (22) to which the cutting accessory and attachment are releasably attached. Collet (50) located inside a drill housing (44) located at one end of the handpiece securely fastens the surgical tool to a motor (24) also located in the handpiece. Leaf spring assembly (46) flush with the drill housing releasably secures the attachment in place. A single actuating collar (52) located around the outside of the drill housing both controls the locking force supplied by the collet and selectively relaxes the leaf spring assembly.

Abstract: Orthopaedic wires, cables, and methods of making them are based on the discovery that, in clinical orthopaedic applications, material toughness and fatigue strength are as important or more important than ultimate tensile strength. The wires and cables of the invention have a tensile strength lower than 280 ksi, but higher than 175 ksi. The presently preferred wires and cables have a tensile strength of 210-240 ksi. The fatigue strength of the wires and cables of the invention is between six and ten times that of other high strength cables used in orthopaedic applications. One method of making the wires and cables includes annealing high tensile strength wire or cable to reduce its tensile strength and thereby increase its fatigue strength. Another method is to cold work fully annealed wire or cable to the extent of decreasing its cross section by approximately 18%.

Abstract: Apparatus for storing, mixing, and dispensing a two-component bone cement includes a first component supply section, a mixing section, and a drive base. One or more ampules of the first (liquid) component, provided within the first component supply section, are broken or cut when a lever is rotted. The second (powder) component is provided within the mixing section. During the mixing process, a vacuum is applied within the mixing section, assisting in the delivery of the first component through a filter while preventing the passage of broken glass or plastic from the ampules. Mixing is done by a pair of paddles and a helical wire spring rotating within the mixing station, being driven in one direction, or in alternating opposite directions of rotation, by the drive base.

Abstract: Disclosed are a family of single-chain polypeptide constructs designed to agonize or mimic members of the TGF-.beta. superfamily by binding to a cell surface receptor complementary to the superfamily member. The single-chain constructs of the invention called "morphons" contain in a single biologically active subunit interacting finger and heel regions which together define a tertiary protein structure complimentary to the ligand binding surface of a receptor that binds a TGF-.beta. superfamily member. Also disclosed are truncated versions of the morphon constructs. Methods are disclosed for making and using single-chain morphons that have binding affinity for predetermined receptors of the TGF-.beta. superfamily.

Abstract: A hand instrument and method for use by a surgeon to target the appropriate entry point and trajectory on bony tissue through which an instrument, such as a nail, pin, screw, rod, wire, drill bit, or other implant is passed. Imbedded within the instrument is at least one relatively radio-opaque target which allows the user to predict with the use of an x-ray or fluoroscopic imaging device the placement of said instrument or implant before drilling it into place with the use of an x-ray or fluoroscopic imaging device. By manipulating the device around the axis of the guide piece, the surgeon can predict the placement of the instrument or implant without iterative insertion and removal of the instrument or implant itself.

Abstract: Disclosed are matrix materials, methods, and devices for manufacture in vivo of autogenous replacement body parts comprising plural distinct tissues. In one embodiment, the replacement body part is a skeletal joint and the new plural distinct tissues include bone and articular cartilage.

Abstract: Disclosed are terminally sterilized osteogenic devices for implantation into a mammal. The devices contain a combination of a biologically active osteogenic protein and an insoluble carrier which after being combined are sterilized by exposure to ionizing radiation, for example, by exposure to gamma rays or an electron beam. The terminally sterilized devices of the invention are characterized in that they induce bone formation following implantation into a mammal. Also disclosed is a method for inducing bone formation in a mammal by implanting a terminally sterilized device of the invention into a preselected locus in a mammal. Also disclosed is a method for preparing the terminally sterilized device of the invention.

Abstract: A motor control chip (62) for asserting the control signals used to regulate the energization of the windings of a DC motor. The motor control chip includes a tachometer (94) that receives pulsed signals that vary with the rotation of the motor rotor and that produces a pulse width modulated tachometer signal as a function of the motor speed. A pulse width modulator (90) receives the tachometer signal and an analog signal representative of the user-selected motor speed. Based on the received input signals, the pulse width modulator produces a variable speed control signal. A forward/reverse oscillator (92) receives user-set signals indicating if the motor should be run in the forward or reverse directions or in an oscillatory pattern. Based on the received signals, the forward/reverse oscillator asserts a forward/reverse signal having an appropriate signal state or cycle. A motor decoder (98) receives the signals produced by the pulse width oscillator and the forward/reverse oscillator.

Abstract: A pulsed irrigation handpiece comprises a pulsed irrigation liquid outlet for applying liquid pulses to a surgical site, a pump unit reciprocatingly driveable for pumping pulses of irrigation liquid through the outlet, an electric powered drive unit for reciprocatingly driving the pump unit, and a housing containing the pump and drive units. A irrigation inlet hose leads from the pump unit out of the handpiece housing and is connectable to a remote irrigation liquid source. An irrigation inlet hose adjacent the remote end thereof and electric conductors extending along the irrigation inlet hose transfer electric power from the supply unit to the drive unit in the handpiece. Removable tips are alternatively removably attachable to the irrigation liquid outlet adjacent the front end of the handpiece.

Abstract: A bone fixing device, in particular for fixing to the sacrum for osteosynthesis of the backbone, comprises elongate link means receiving at least one bone-fastening screw, which passes through an orifice formed in the link means. In the bottom of the link means there is included a bearing surface of essentially circular cross-section. The head of the screw includes an essentially spherical surface for bearing against said bearing surface. The link means include a first thread in the vicinity of said orifice. The device further includes a plug having a second thread suitable for co-operating with the first thread, the plug being suitable for coming into clamping contact against said screw head to hold it in a desired angular position. According to the invention, the link means are constituted by a single-piece plate-shaped element having the orifice and the first thread formed therein, and said bearing surface is essentially spherical.

Abstract: A device for use with an acetabular socket prosthesis which has an outer rim of predetermined size. The device comprises an outwardly extending removable location and/or sealing element adapted to surround the outer rim of said cup with which it is to be used during implantation thereof.

Abstract: A battery charger (20) for charging batteries to which different charging currents are applied in different instruction sequences. The charger includes a microprocessor (124) that controls the generation of current by a current source (110). A removable module (26) is attached to the charger for holding a particular type of battery. A memory (70) internal to the module contains data indicating the sequences in which charging currents are to be applied to the battery and when tests should be executed to determine if the battery should exit a particular charging step. The module memory also contains data indicating the currents that should be applied to the battery with which it is associated and the parameters of the exit condition tests. The charger is ideally used with a battery that has both and internal temperature sensor (286) and its own memory (282). The temperature sensor provides data useful for accurately determining the stored charge within the battery.

Abstract: An integrated surgical tool system (30) for energizing different powered surgical handpieces (32, 33). Internal to each handpiece is a non-volatile memory (72) which stores data regarding the operating parameters of the handpiece. This data, includes information about the speeds at which any motor internal to the handpiece should be driven, the maximum current that should be drawn by the handpiece and the maximum internal temperature of the handpiece. The handpiece is plugged into a complementary control console (36). The control console reads the data in the internal memory. Based on the retrieved data and manual control signals, the control console supplies energization signals to the handpiece so as to cause the appropriate actuation of the handpiece.

Abstract: Disclosed are terminally sterilized osteogenic devices for implantation into a mammal. The devices contain a combination of a biologically active osteogenic protein and an insoluble carrier which after being combined are sterilized by exposure to ionizing radiation, for example, by exposure to gamma rays or an electron beam. The terminally sterilized devices of the invention are characterized in that they induce bone formation following implantation into a mammal. Also disclosed is a method for inducing bone formation in a mammal by implanting a terminally sterilized device of the invention into a preselected locus in a mammal. Also disclosed is a method for preparing the terminally sterilized device of the invention.

Abstract: A motor controller for regulating the application of current to the windings of a motor in order to both control the actuation of the motor rotor and the braking of the rotor. The motor controller includes a speed control circuit regenerating a signal representative of the user-selected speed, a direction controller to signal if the motor is to be driven in the forward, reverse or oscillatory motion and a speed override circuit. There is also a current sensor for monitoring the current drawn by the motor, a brake controller and an energization circuit. The energization circuit regulates the application of a current to the motor to cause the rotation or braking of the rotor. When the motor is to be oscillated, each time the direction controller circuit transitions a FORWARD/REVERSE signal, the speed override circuit causes the energization circuit to momentarily apply energization signals to the motor based on the application of a zero-speed, user-speed signal.

Abstract: An irrigation surgical tool system comprises a motorized handpiece, a tool for insertion in the handpiece, a console including a mounting plate and peristaltic pump rotor and a tube set including a cassette installable on the console for peristaltic pumping of irrigation liquid to the tool. Passages in the tool allow irrigation liquid flow, between a fixed outer tube and rotating inner tube of the tool, to a surgical site, through windows in the tool inner and outer tubes. Application of suction to the tool enables withdrawal through the inner tube of irrigation and surgical debris from the surgical site.

Abstract: An improved asymmetric femoral hip stem component for use in cementless hip replacement procedures is described. The stem comprises a proximal region having a novel three-dimensional configuration to allow for better fit and stability of the stem within the femoral intramedullary canal with minimal removal of strong bone therefrom. The stem further includes a twist isolated in the mid-stem region to improve fit while minimizing enlargement of the femoral canal. A distal end comprising a rotated internal slot is also described, wherein the slot reduces bending stiffness of the stem in both the coronal and sagittal planes.

Abstract: A ratcheting compression device is provided which is very strong, which can be customized in length, which can be retightened periodically to maintain compression, which allows precise placement and alignment of bones with both grossly tuned compression and finely tuned compression, and in which only a limited inventory of parts is required. The two-piece compression device comprises (a) a novel first piece having a bone screw located at a first end thereof and having a ratcheting means located near the second end thereof and comprising teeth having their crests lying substantially in a plane and (b) a novel second piece comprising an anti-rotation means which acts in cooperation with the ratcheting means of the first piece to compress two segments of bone together.In yet other embodiments, two embodiments of a driver are provided for quickly driving the stop onto the ratcheting means to a desired extent.

Abstract: A blade guard (12) for preventing a saw blade (16) or other cutting member from cutting into tissue the cutting member is not intended to cut. The blade guard includes a body (20) that is attached to the surgical tool (10) from which the cutting member extends. A leg (24) extends from the body. A foot (34) is attached to the end of the leg. The foot encapsulates the end of the cutting member to prevent it from penetrating into tissue the cutting member is not intended to cut. The leg is formed with a tapered profile such that it has a leading edge (29) adjacent the cutting member that is narrow in width than the trailing edge (30) spaced from the cutting member. The tapered profile of the leg provides the leg with structural strength. The tapered profile also facilitates the separation of the sections of the bone that define the kerf as the cutting member and blade guard pass through the bone.

Abstract: A patient support stretcher which includes a base and a main frame portion coupled to the base through at least one pair of crossbars forming an X-shaped configuration. The crossbars are pivotally connected to one another and are pivotally connected to the base and the main frame portion. A back support or a fowler section is hinged to the main frame portion and a strut interconnects the back support to the main frame to provide the requisite balanced leverage for effecting the simultaneous lift of the main frame and the fowler section.