Abstract: The present invention relates to a device for detecting an analyte in a sample, of which the sensitivity is improved by changing the structure. The device for detecting analyte in a sample of the present invention has the effect of improving measurement sensitivity and accuracy by arranging a light source and a photosensor to correspond to an inspection area and a control area, forming holes at positions corresponding to respective light source units, the photosensor, the inspection area, and a calibration area, and adding a stick housing having stick housing partitions formed around the holes.

Abstract: A fluorescent standard strip, according to the present invention, is for testing the reliability of the fluorescence intensity of a fluorescent strip used for an analyzer, the fluorescent standard strip having an effect whereby, for devices using a fluorescent substance, the inter-device deviation in fluorescence intensity is reduced, fluorescent signal linearity per fluorescent concentration level is secured, and device reliability may be tested by periodically checking faults, errors, deviations, etc. of the devices. In addition, the fluorescent standard strip, according to the present invention, has an effect whereby, even in an environment and state where light is frequently irradiated, the reduction of fluorescence intensity according to time may be minimized, i.e., the same level of fluorescence intensity may be maintained for a long period.

Abstract: A fluorescent standard strip, according to the present invention, is for testing the reliability of the fluorescence intensity of a fluorescent strip used for an analyzer, the fluorescent standard strip having an effect whereby, for devices using a fluorescent substance, the inter-device deviation in fluorescence intensity is reduced, fluorescent signal linearity per fluorescent concentration level is secured, and device reliability may be tested by periodically checking faults, errors, deviations, etc. of the devices. In addition, the fluorescent standard strip, according to the present invention, has an effect whereby, even in an environment and state where light is frequently irradiated, the reduction of fluorescence intensity according to time may be minimized, i.e., the same level of fluorescence intensity may be maintained for a long period.

Abstract: A specimen tube holder includes a probe-type capacitance liquid level detection sensor having increased sensitivity and thus enables more precise liquid level recognition. A specimen tube holder includes: a central holder; and a lateral holder which is made of a conductive material, is spaced apart from a side surface of the central holder so as to have a receiving space formed between the central holder and the lateral holder to allow a specimen tube to be inserted into the receiving space, and has an inner surface formed to be vertically in contact with at least a part of the outer circumferential surface of the specimen tube received in the receiving space.

Abstract: A method for diagnosing tuberculosis of the present invention can improve the reactivity of tuberculous antigens and detection antibodies by increasing free tuberculous antigens in a sample through a pretreatment step in which the sample of a subject is treated with an acidic material such that the antigens are dissociated from tuberculous antigen complexes, thereby enabling a point-of-care test for tuberculosis and being immediately utilizable as a fast and simple detection method for a point-of-care test.

Abstract: A probe system for real-time quantitative and qualitative analysis of a biomaterial, and a reaction chamber with the probe system, and an analysis method thereof are provided. The probe system, which is included in the reaction chamber having an optically transmissive flat bottom surface and having a test sample accommodated therein, includes a target probe-reporter probe linker accommodated in the reaction chamber and including a target probe, which includes a sequence complementary to a target nucleic acid sequence to be detected, a first fluorophore and a first quencher, and a reporter probe linked to an end of the target probe and including a sequence non-complementary to the target nucleic acid sequence, and a capture probe included in a biochip formed on a bottom surface of the reaction chamber and including a complementary sequence hybridizable with the non-complementary sequence of the reporter probe, a second fluorophore and a second quencher.

Abstract: A method of quantitatively and qualitatively analyzing a biomaterial in real-time, the method comprising preparing a device for detecting a biomaterial, feeding a complex of first and second probes, a forward primer, a reverse primer, a sample comprising deoxynucleotide triphosphate, a polymerase having exonuclease activity, and a sample comprising target genes, and a reaction solution comprising a buffer into the reaction container, performing polymerase chain reaction comprising denaturation of the target genes in the sample, hybridization of the target genes, the complex, and the forward and reverse primers in the sample, and elongation of the primers through the polymerase having exonuclease activity, allowing for elongation of the second probe on the third probe by the polymerase after hybridizing the released second probe and the third probe fixed to the biochip, detecting a first fluorescence signal by the first phosphor and a second fluorescence signal by the second phosphor.

Abstract: A device for detecting analytes in a sample includes (a) n light source units generating light; (b) a reaction strip including (i) a test area illuminated with light from the light source unit and including a material reacting to the analytes, (ii) a control area illuminated with the light from the light source unit and including a control material, and (iii) a background area illuminated with the light from the light source unit; and (c) at least n+1 light receiving units detecting light emitted from the test area, the control area, and the background area of the reaction strip, respectively.

Abstract: Disclosed is a method for detecting nucleic acids by promoting branched DNA complex formation. The target nucleic acid detection signal and sensitivity can be dramatically increased by promoting self assembly of branched DNA between a plurality of amplified DNA targets and a single-chain oligonucleotide probe, by means of the integrated implementation of PCR, thermal denaturation and hybridization in a single reaction mixture.

Abstract: A device for detecting analytes in a sample includes (a) n light source units generating light; (b) a reaction strip including (i) a test area illuminated with light from the light source unit and including a material reacting to the analytes, (ii) a control area illuminated with the light from the light source unit and including a control material, and (iii) a background area illuminated with the light from the light source unit; and (c) at least n+1 light receiving units detecting light emitted from the test area, the control area, and the background area of the reaction strip, respectively.