Patents Assigned to Sumner M. Kalman
  • Cardioactive factor
    Patent number: 4339441
    Abstract: A proteinaceous cardioactive factor that exhibits positive inotropic activity and positive chronotropic activity has been partially extracted from mammalian plasma by precipitation with polyethylene glycol followed by cation exchange chromatography. The factor may be fractionated into two active fractions, one having an apparent molecular weight of about 130,000 daltons and the other having an apparent molecular weight of about 30,000 daltons, by gel filtration chromatography.
    Type: Grant
    Filed: October 30, 1981
    Date of Patent: July 13, 1982
    Assignee: Sumner M. Kalman
    Inventors: Sumner M. Kalman, Ruth M. Jones