Abstract: This invention to a process of extracting and purifying biologically effective ingredients from combined medicinal plants and their plant extract composition and more particularly, to a process for effective extracting and purifying the biologically effective ingredients by mixing Clematis Radix, Trichosanthes root and Prunella Herba in a certain ratio, being useful for alleviating acute/chronic inflammation and also for inhibiting platelet/whole blood aggregation, abnormally proliferated immunocytes (e.g., B-lymphocyte, T-lymphocyte), inflammation-inducing enzymes (5-Lipoxygenase, Cyclooxygenase-I, Cyclooxygenase-II) and also scavenging activity on toxic active oxygen species when compared to a single plant extracts, together with their extract composition, which may be effectively used as an anti-inflammatory agent with analgesic effects, rheumatoid arthritis drug and agents for improving peripheral blood circulation.

Abstract: An Escherichia coli (ATCC 68319) containing a gene encoding a novel maltogenic amylase of Bacillus licheniformis (BLMA), wherein said gene has a length of about 3.5 kb; said gene expresses a gene product capable of hydrolyzing cyclodextrin, pullulan, as well as starch at an optimum temperature of about 50.degree. C. at a pH of about 7; said gene product has sugar transferase activity in the presence of glucose; and said Escherichia coli produces said gene product optimally when grown in Luria broth, for 24 hours, at 37.degree. C.

Abstract: Disclosed herein are novel platinum(II) complexes having a potent anti-tumor activity which are represented by the formula (1), ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, are a hydrogen atom or a C.sub.1-4 alkyl group, respectively, or jointly form a cycloalkane group together with the carbon atom attached thereto; two Xs jointly form a group represented by formula (a) or (b) wherein, R.sub.3 is a hydrogen atom or a methyl group; R.sub.4 and R.sub.5, which may be the same or different, are a hydrogen atom or a C.sub.1-4 alkyl group, respectively, or jointly form a cyclobutane together with the carbon thereto; and the absolute configurations at the respective chiral centers in the 4,5-bis(aminomethyl)-1,3-dioxolane moiety are (4R,5R) or (4S,5S); processes for the preparing the same; and their use for treating animal or human cancer.

Abstract: A method of isolating ginkgolides from the leaves of the Ginkgo tree which is characterized by a series of steps as follows:(a) Adjusting the pH of an aqueous solution of an extract of the leaves of the Ginkgo tree to the range of 7 to 9 by adding an alkaline aqueous solution,(b) Extracting the aqueous solution treated as above with lower acetates, lower ketones or benzenes, separate the solution into a layer of aqueous solution and a layer of organic solvent, dehydrating and drying the layer of organic solvent, and obtaining a powder,(c) Adjusting the pH of the layer of aqueous solution separated in step (b), to the range of 1 to 3 by adding an acidic aqueous solution, extracting the layer of aqueous solution treated as above with lower ethers or chloroforms, dehydrating and drying the obtained extract,(d) Dissolving the dry powder obtained the step (b) and the residue obtained in the step (c) in a lower alcohol,(c) Adding an aqueous solution of lead acetate to the solution obtained in the step (d), removing