Patents Assigned to Suomen Punainen Risti Veripalvelu
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Patent number: 8703488Abstract: The invention relates to a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) cells on a lectin. The invention relates also to the use of a lectin in a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) celts and a culture medium composition containing a lectin attached on the culturing plates.Type: GrantFiled: July 13, 2009Date of Patent: April 22, 2014Assignees: Suomen Punainen Risti Veripalvelu, Glykos Finland OyInventors: Ulla Impola, Minna Tiittanen, Milla Mikkola, Jukka Partanen, Jari Natunen, Tero Satomaa, Juhani Saarinen
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Publication number: 20130230859Abstract: The present invention relates to use of the non-secretor/secretor blood group status of an individual as a criterion for need of Lactobacillus/LAB-enriched probiotic supplementation. The present invention relates also to method of assessing the need of an individual for Lactobacillus/LAB-enriched probiotic supplementation by determining the secretory blood group status of the individual.Type: ApplicationFiled: July 26, 2011Publication date: September 5, 2013Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo Wacklin, Jaana Mättö, Harri Mäkivuokko, Jukka Partanen
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Publication number: 20130195820Abstract: The present invention relates to a microbial composition which is tailored based on the spectrum of microbes found more frequently from the intestine of non-secretor individuals than from the intestine of secretor individuals. The present invention further relates to a method of tailoring a microbial composition based on the spectrum of microbes found more frequently from the intestine of non-secretor individuals than from that of secretor blood group status. The present invention relates to use of the secretor status of an individual as a criterion for microbial supplementation tailored based on the differences in the spectra of microbes found between secretor and non-secretor individuals.Type: ApplicationFiled: July 26, 2011Publication date: August 1, 2013Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo Wacklin, Jaana Matto, Harri Makivuokko, Jukka Partanen, Janne Nikkila
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Patent number: 8440457Abstract: The present invention relates to a method of profiling a cell population comprising a step of detecting the presence or absence of at least two biological markers in said cell population, wherein at least one of said markers is a cell surface marker, which is a sialylated N-glycan marker with structure NeuNAc?3Gal, and at least one of said markers is a mRNA marker related to glycoproteins and/or glycosynthase proteins. The invention also relates to method for purification of cord blood cell population and to a complete cell population from cord blood purified by said method.Type: GrantFiled: June 6, 2006Date of Patent: May 14, 2013Assignees: Suomen Punainen Risti, Veripalvelu, Glykos Finland OyInventors: Taina Jaatinen, Heidi Anderson, Jukka Partanen, Jarmo Laine, Tero Satomaa, Jari Natunen, Maria Blomqvist
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Publication number: 20130101560Abstract: The present invention relates to use of the ABO blood group genotype of an individual as a criterion for microbiota modulation that is tailored based on the differences in the spectrum of bacteria found between individuals with different ABO blood group genotypes. The present invention relates further to a microbial composition tailored based on the microbial genotypes shown to be specific for A, B, and/or O blood groups.Type: ApplicationFiled: June 13, 2011Publication date: April 25, 2013Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Harri Makivuokko, Jaana Matto, Pirjo Wacklin, Jukka Partanen, Jarkko Rabina
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Publication number: 20130034901Abstract: The present invention relates to a stem cell and/or a population thereof having a specific profile of cell surface proteins and/or proteoglycans. The present invention also relates to use of a proteolytic enzyme in the modification of the cell surface of a stem cell. The present invention further relates to a method of modifying the cell surface of a stem cell by treatment with a proteolytic enzyme.Type: ApplicationFiled: April 6, 2011Publication date: February 7, 2013Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Johanna Nystedt, Tanja Hakkarainen, Petri Lehenkari, Erja Kerkelä, Leena Valmu
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Publication number: 20120315250Abstract: The present invention relates to a probiotic composition which is tailored based on the spectrum of bifidobacteria found in the intestine of at least one individual with non-secretor blood group phenotype. The present invention further relates to a method of tailoring a probiotic composition based on the bifidobacteria found from the intestine of at least one non-secretor individual.Type: ApplicationFiled: December 28, 2010Publication date: December 13, 2012Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo Wacklin, Jaana Mättö, Harri Mäkivuokko
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Publication number: 20120301435Abstract: The present invention relates to a microbial or probiotic composition which is tailored based on the spectrum of bifidobacteria found in the intestine of at least one individual with secretor blood group phenotype but not commonly found in individuals of non-secretor blood group phenotype. The present invention further relates to a method of tailoring a microbial or probiotic composition based on the bifidobacteria found in the intestine of at least one individual with secretor blood group phenotype but not commonly found in individuals non-secretor blood group phenotype.Type: ApplicationFiled: December 28, 2010Publication date: November 29, 2012Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo Wacklin, Jaana Matto, Harri Makivuokko
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Publication number: 20120202701Abstract: Antibody-saccharide-complexes and methods and uses related to analysis of cells. Also disclosed is a method of selection of new antibody with CHO-specificity and to a use of antibodies produced for the analysis of stem cells or cancer cells or other cells or tissues known to bind to CHO-antibodies.Type: ApplicationFiled: April 23, 2010Publication date: August 9, 2012Applicants: GLYKOS FINLAND OY, SUOMEN PUNAINEN RISTI, VERIPALVELUInventors: Suvi Natunen, Johanna Nystedt, Heidi Anderson, Jari Natunen
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Publication number: 20120190058Abstract: The invention describes specific sialylated structures present on human stem cells and cell populations derived thereof. The invention is especially directed to methods to control the status of stem cells by observing changes in sialylation of the cells; and control of potential contaminations of biological materials; and reagents and methods used in connection with the cells in order to avoid alterations of the cell glycosylation by contaminating materials. The invention is further directed to novel stem cells, the glycosylation of which has been specifically altered.Type: ApplicationFiled: January 17, 2012Publication date: July 26, 2012Applicants: Glykos Finland Oy, SUOMEN PUNAINEN RISTI, VERIPALVELUInventors: Jarmo Laine, Taina Jaatinen, Heidi Anderson, Johanna Nystedt, Sari Tiitinen, Anita Laitinen, Ulla Impola, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen
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Publication number: 20120129712Abstract: A complex of Tra-antibody bound to an isolated glycan comprising type I—N-acetyllactosamine comprising target structure, and methods and uses utilizing said complex.Type: ApplicationFiled: April 26, 2010Publication date: May 24, 2012Applicants: GLYKOS FINLAND OY, SUOMEN PUNAINEN RISTI, VERIPALVELUInventors: Tero Satomaa, Suvi Natunen, Leena Valmu, Jari Natunen
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Publication number: 20120115180Abstract: The present invention relates to an in vitro and/or ex vivo method of screening probiotic bacterial strains. The present invention also relates to a method of assessing quality of probiotic culture. In addition, the present invention relates to use of animal cells in screening of a probiotic strain. The present invention also relates to use of animal cells in assessing quality of probiotic culture.Type: ApplicationFiled: July 14, 2010Publication date: May 10, 2012Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Kaarina Lähteenmäki, Jaana Mättö, Harri Mäkivuokko, Jukka Partanen
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Patent number: 8110366Abstract: The invention describes specific sialylated structures present on human stem cells and cell populations derived thereof. The invention is especially directed to methods to control the status of stem cells by observing changes in sialylation of the cells; and control of potential contaminations of biological materials; and reagents and methods used in connection with the cells in order to avoid alterations of the cell glycosylation by contaminating materials. The invention is further directed to novel stem cells, the glycosylation of which has been specifically altered.Type: GrantFiled: July 7, 2006Date of Patent: February 7, 2012Assignees: Suomen Punainen Risti, Veripalvelu, Glykos Finland OyInventors: Jarmo Laine, Taina Jaatinen, Heidi Anderson, Johanna Nystedt, Sarl Tiitinen, Anita Laitinen, Ulla Impola, Tero Satomaa, Jari Natunen, Annamari Heiskanen, Maria Blomqvist, Anne Olonen
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Publication number: 20120020941Abstract: Provided is a microbial composition which is tailored based on the spectrum of microbes found more frequently from the intestine of non-secretor individuals than from the intestine of secretor individuals. Further provided is a method of tailoring a microbial composition based on the spectrum of microbes found more frequently from the intestine of non-secretor individuals than from that of secretor blood group status. Further provided is a use of the secretor status of an individual as a criterion for microbial supplementation tailored based on the differences in the spectra of microbes found between secretor and non-secretor individuals.Type: ApplicationFiled: July 26, 2010Publication date: January 26, 2012Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo WACKLIN, Jaana MÄTTÖ, Harri MÄKIVUOKKO, Jukka PARTANEN
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Publication number: 20110306128Abstract: The invention relates to a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) cells on a lectin. The invention relates also to the use of a lectin in a method for culturing human embryonic stem cells (hESCs) and/or induced pluripotent stem (iPS) celts and a culture medium composition containing a lectin attached on the culturing plates.Type: ApplicationFiled: July 13, 2009Publication date: December 15, 2011Applicants: GLYKOS FINLAND OY, SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Ulla Impola, Minna Tiittanen, Milla Mikkola, Jukka Partanen, Jari Natunen, Tero Satomaa, Juhani Saarinen
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Publication number: 20110274646Abstract: The present invention relates to a combination of a hyaluronan oligomer and/or polymer and a factor capable of mobilizing stem cells. The present invention also relates to a method for altering the relative amounts of blood cells and/or the types of blood cells in a subject by administering the combination to the subject. Further, the present invention relates to a method for mobilizing stem cells to the bloodstream of a subject by administering the combination to the subject. Additionally, the present invention relates to a hyaluronan oligomer and/or polymer.Type: ApplicationFiled: May 6, 2011Publication date: November 10, 2011Applicants: Glykos Finland Oy, Suomen Punainen Risti VeripalveluInventors: Johanna Nystedt, Heidi Anderson, Tero Satomaa, Jari Natunen, Jari Helin, Juhani Saarinen
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Publication number: 20110217724Abstract: Provided is a method for protecting stem cells in a clinical graft against destruction induced by the complement system by adding to the graft at least one factor capable of inhibiting the complement. Also provided is a method for protecting stem cells in a clinical graft against destruction induced by the complement system using a factor capable of inhibiting the complement.Type: ApplicationFiled: October 15, 2009Publication date: September 8, 2011Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Taina Jaatinen, Seppo Meri, Sami Junnikkala, Jarmo Laine, Jukka Partanen
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Publication number: 20110158951Abstract: Provided is a microbial or probiotic composition which is tailored based on the spectrum of bifidobacteria found in the intestine of at least one individual with secretor blood group phenotype but not commonly found in individuals of non-secretor blood group phenotype. Further provided is a method of tailoring a microbial or probiotic composition based on the bifidobacteria found in the intestine of at least one individual with secretor blood group phenotype but not commonly found in individuals non-secretor blood group phenotype.Type: ApplicationFiled: July 26, 2010Publication date: June 30, 2011Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo Wacklin, Jaana MÄTTÖ, Harri MÄKIVUOKKO
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Publication number: 20110158950Abstract: Provided is a probiotic composition which is tailored based on the spectrum of bifidobacteria found in the intestine of at least one individual with non-secretor blood group phenotype. Further provided is a method of tailoring a probiotic composition based on the bifidobacteria found from the intestine of at least one non-secretor individual.Type: ApplicationFiled: July 26, 2010Publication date: June 30, 2011Applicant: SUOMEN PUNAINEN RISTI VERIPALVELUInventors: Pirjo WACKLIN, Jaana MÄTTÖ, Harri MÄKIVUOKKO
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Publication number: 20110143373Abstract: The invention describes novel reagents that can be applied for analysis of the quality of human cells. The method evaluates the integrity of the plasma membrane of the cells by detecting novel glyco structures found only intracellularly. The method can be applied, for example, to demonstrate exposure of therapeutic cell preparation to potentially harmful conditions. It can also be used as a quality control tool in methods in which intact cell membrane is essential and it can be applied in separation of damaged cells from non- damaged.Type: ApplicationFiled: July 16, 2009Publication date: June 16, 2011Applicants: SUOMEN PUNAINEN RISTI, VERIPALVELU, GLYKOS FINLAND LTDInventors: Tia Hirvonen, Annika Kotovuori, Virve Pitkanen, Suvi Natunen, Johanna Nystedt, Sari Tiitinen, Leena Valmu, Jari Natunen