Abstract: Provided herein are genetic markers for predicting response to antipsychotic treatment. Identification of the disclosed SNPs can be used to predict response to antipsychotic drugs in patients suffering from schizophrenia.
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a OPRP genetic signature are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the genetic signature.
Type:
Application
Filed:
October 7, 2011
Publication date:
April 11, 2013
Applicant:
SUREGENE, LLC
Inventors:
Timothy L. Ramsey, Bharat Mehrotra, Mark D. Brennan
Abstract: This document provides methods and materials related to genetic markers of Bipolar Disorder (BD) and Schizophrenia (SZ). For example, methods for using such genetic markers to assess risk of developing BD and/or SZ are provided, as are methods for making a differential diagnosis between BD and SZ.
Type:
Application
Filed:
January 27, 2012
Publication date:
May 24, 2012
Applicant:
SureGene, LLC
Inventors:
Mark David Brennan, Timothy Lynn Ramsey
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a OPRP genetic signature are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the genetic signature.
Type:
Application
Filed:
April 25, 2011
Publication date:
April 19, 2012
Applicant:
SUREGENE, LLC
Inventors:
Timothy L. Ramsey, Bharat Mehrotra, Mark D. Brennan
Abstract: This document provides methods and materials related to genetic markers of schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective disorder (SD), (collectively referred to herein as “schizophrenia spectrum disorders” or SSDs). For example, methods for using such genetic markers to identify an SSD (e.g., SZ) endophenotype are provided.
Type:
Grant
Filed:
November 4, 2009
Date of Patent:
February 14, 2012
Assignee:
SureGene, LLC
Inventors:
Mark David Brennan, Timothy Lynn Ramsey
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1 haplotype are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the haplotype status.
Abstract: Methods and compositions that relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1 haplotype are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the haplotype status.
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1 haplotype are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the haplotype status.
Abstract: Methods and compositions that relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1 haplotype are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the haplotype status.
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a OPRP genetic signature are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the genetic signature.
Type:
Grant
Filed:
October 13, 2010
Date of Patent:
April 26, 2011
Assignee:
Suregene, LLC
Inventors:
Timothy L. Ramsey, Bharat Mehrotra, Mark D. Brennan
Abstract: Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a SULT4A1-1 haplotype are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the haplotype status.
Abstract: This document provides methods and materials related to genetic markers of schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective disorder (SD), (collectively referred to herein as “schizophrenia spectrum disorders” or SSDs). For example, methods for using such genetic markers to identify an SSD (e.g., SZ) endophenotype are provided.
Type:
Application
Filed:
November 4, 2009
Publication date:
May 13, 2010
Applicant:
SUREGENE, LLC
Inventors:
Mark David Brennan, Timothy Lynn Ramsey
Abstract: This document provides methods and materials related to genetic markers of Bipolar Disorder (BD) and Schizophrenia (SZ). For example, methods for using such genetic markers to assess risk of developing BD and/or SZ are provided, as are methods for making a differential diagnosis between BD and SZ.
Type:
Application
Filed:
November 4, 2009
Publication date:
May 13, 2010
Applicant:
SUREGENE, LLC
Inventors:
Mark David Brennan, Timothy Lynn Ramsey