Patents Assigned to Surface Oncology, LLC
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Publication number: 20260167716Abstract: The present disclosure relates to methods of treating a tumor in a subject in need thereof comprising administering an IL-27 inhibiting agent, wherein the subject is identified as having a tumor that (i) expresses WSX-1, (ii) comprises one or more immune cell that expresses IL-27, (iii) or both (i) and (ii).Type: ApplicationFiled: October 30, 2023Publication date: June 18, 2026Applicant: SURFACE ONCOLOGY, LLCInventors: Ricard MASIA, Jonathan HILL, Secil KOSEOGLU, Benjamin H. LEE, Yu YANG
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Patent number: 12630624Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.Type: GrantFiled: April 6, 2022Date of Patent: May 19, 2026Assignee: SURFACE ONCOLOGY, LLCInventors: Jonathan Hill, Scott Chappel, Michael Gladstone, Bianka Prinz, Andrew Lake, Christine Miller, Kerry White, Jing Hua, Pamela M. Holland, Matthew Rausch, Devapregasan Moodley
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Patent number: 12577299Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof at a dose of at least about 0.003 mg/kg to at least about 20 mg/kg.Type: GrantFiled: May 6, 2022Date of Patent: March 17, 2026Assignee: SURFACE ONCOLOGY, LLCInventors: Alison O'Neill, Lauren Harshman, Jonathan Hill, Jou-Ku Chung, Kerry White, Robert Ross, Benjamin Lee
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Publication number: 20260055176Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.Type: ApplicationFiled: June 12, 2025Publication date: February 26, 2026Applicant: Surface Oncology, LLCInventors: Jonathan HILL, Scott CHAPPEL, Michael GLADSTONE, Bianka PRINZ, Andrew LAKE, Christine MILLER, Kerry WHITE, Jing HUA, Pamela M. HOLLAND, Matthew RAUSCH, Devapregasan MOODLEY, Gege TAN
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Patent number: 12358978Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.Type: GrantFiled: September 25, 2019Date of Patent: July 15, 2025Assignee: SURFACE ONCOLOGY, LLCInventors: Jonathan Hill, Scott Chappel, Michael Gladstone, Bianka Prinz, Andrew Lake, Christine Miller, Kerry White, Jing Hua, Pamela M. Holland, Matthew Rausch, Devapregasan Moodley, Gege Tan
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Publication number: 20250154244Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.Type: ApplicationFiled: January 17, 2025Publication date: May 15, 2025Applicant: SURFACE ONCOLOGY, LLCInventors: Jonathan HILL, Scott CHAPPEL, Michael GLADSTONE, Bianka PRINZ, Andrew LAKE, Christine MILLER, Kerry WHITE, Jing HUA, Pamela M. HOLLAND, Matthew RAUSCH, Devapregasan MOODLEY
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Publication number: 20250051449Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.Type: ApplicationFiled: October 29, 2024Publication date: February 13, 2025Applicant: Surface Oncology, LLCInventors: Bianka PRINZ, Nadthakarn BOLAND, Kevin SCHUTZ, John BUKOWSKI, Jennifer SYMONDS, James MOHAN, Marisella Panduro SICHEVA
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Patent number: 12162941Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.Type: GrantFiled: November 19, 2021Date of Patent: December 10, 2024Assignee: Surface Oncology, LLCInventors: Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva
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Publication number: 20240199732Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.Type: ApplicationFiled: April 27, 2023Publication date: June 20, 2024Applicant: Surface Oncology, LLCInventors: Jamie Strand, Jonathan Hill, Devan Moodley