Patents Assigned to Surrozen Operating Inc.
  • Liver-specific Wnt signal enhancing molecules and uses thereof
    Patent number: 12240876
    Abstract: The present disclosure provides liver-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in liver tissues and treat liver diseases and disorders.
    Type: Grant
    Filed: May 2, 2023
    Date of Patent: March 4, 2025
    Assignee: Surrozen Operating, Inc.
    Inventors: Yang Li, Zhengjian Zhang, Randall J. Brezski, Leonard Presta, Thomas Lopez, Hui Chen, Helene Baribault, Wen-Chen Yeh, Shengjiang Tu
  • Anti-frizzled antibodies and methods of use
    Patent number: 12006368
    Abstract: The present invention provides anti-Fzd monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: June 11, 2024
    Assignee: Surrozen Operating, Inc.
    Inventors: Yang Li, Tom Zhiye Yuan, Aaron Ken Sato, Wen-Chen Yeh, Chenggang Lu, Parthasarathy Sampathkumar, Claudia Yvonne Janda
  • ANTI-LRP5/6 ANTIBODIES AND METHODS OF USE
    Publication number: 20240150458
    Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.
    Type: Application
    Filed: July 11, 2023
    Publication date: May 9, 2024
    Applicant: Surrozen Operating, Inc.
    Inventors: Yang LI, Tom Zhiye YUAN, Aaron Ken SATO, Wen-Chen YEH, Parthasarathy SAMPATHKUMAR
  • Tissue-specific Wnt signal enhancing molecules and uses thereof
    Patent number: 11958891
    Abstract: The present disclosure provides tissue-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in targeted tissues.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: April 16, 2024
    Assignee: Surrozen Operating, Inc.
    Inventors: Zhengjian Zhang, Jennifer Jean Brady, Aaron Ken Sato, Wen-Chen Yeh, Yang Li, Teppei Yamaguchi
  • LIVER-SPECIFIC WNT SIGNAL ENHANCING MOLECULES AND USES THEREOF
    Publication number: 20230374090
    Abstract: The present disclosure provides liver-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in liver tissues and treat liver diseases and disorders.
    Type: Application
    Filed: May 2, 2023
    Publication date: November 23, 2023
    Applicant: Surrozen Operating, Inc.
    Inventors: Yang LI, Zhengjian ZHANG, Randall J. BREZSKI, Leonard PRESTA, Thomas LOPEZ, Hui CHEN, Helene BARIBAULT, Wen-Chen YEH, Shengjiang TU
  • WNT surrogate molecules and uses thereof
    Patent number: 11773171
    Abstract: The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: October 3, 2023
    Assignee: Surrozen Operating, Inc.
    Inventors: Yang Li, Tom Zhiye Yuan, Aaron Ken Sato, Wen-Chen Yeh, Claudia Yvonne Janda, Tristan William Fowler, Helene Baribault, Kuo-Pao Lai, Liqin Xie, Randall J. Brezski, Chenggang Lu
  • Anti-LRP5/6 antibodies and methods of use
    Patent number: 11746150
    Abstract: The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: September 5, 2023
    Assignee: Surrozen Operating, Inc.
    Inventors: Yang Li, Tom Zhiye Yuan, Aaron Ken Sato, Wen-Chen Yeh, Parthasarathy Sampathkumar
  • MODULATION OF WNT SIGNALING IN GASTROINTESTINAL DISORDERS
    Publication number: 20220195053
    Abstract: The present invention provides methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway. Also provided are methods of dosing and pharmaceutical compositions.
    Type: Application
    Filed: March 11, 2020
    Publication date: June 23, 2022
    Applicant: Surrozen Operating Inc.
    Inventors: Yang LI, Chenggang LU, Hélène BARIBAULT, Wen-Chen YEH, Liqin XIE, I-Chieh WANG, Weixu MENG