Patents Assigned to Sutter West Bay Hospitals
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Patent number: 9920377Abstract: The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of BPTF. The disclosure also provides methods for determining whether a cancer in a subject is progressing or regressing based upon the change of expression levels of BPTF between two time points. The disclosure further provides methods to treat a subject with a cancer by administering a polynucleotide comprising an inhibitory BPTF nucleic acid and/or an agent that inhibits the expression or activity of BPTF.Type: GrantFiled: March 15, 2014Date of Patent: March 20, 2018Assignee: SUTTER WEST BAY HOSPITALSInventors: Mohammed Kashani-Sabet, Altaf A. Dar
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Patent number: 9809521Abstract: The disclosure relates to cannabinoid derivative compounds, pharmaceutical compositions made thereof, and methods for treating various diseases and disorders including cancer.Type: GrantFiled: January 25, 2016Date of Patent: November 7, 2017Assignee: SUTTER WEST BAY HOSPITALSInventors: Sean D. McAllister, Pierre-Yves Desprez, Anuradha Mahadevan
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Patent number: 9340788Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).Type: GrantFiled: May 3, 2013Date of Patent: May 17, 2016Assignee: Sutter West Bay HospitalsInventors: Charles Cobbs, Liliana Soroceanu
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Patent number: 9254272Abstract: The disclosure relates to cannabinoid derivative compounds, pharmaceutical compositions made thereof, and methods for treating various diseases and disorders including cancer.Type: GrantFiled: November 30, 2012Date of Patent: February 9, 2016Assignee: Sutter West Bay HospitalsInventors: Sean D. McAllister, Pierre-Yves Desprez, Anuradha Mahadevan
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Publication number: 20160024590Abstract: The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of BPTF. The disclosure also provides methods for determining whether a cancer in a subject is progressing or regressing based upon the change of expression levels of BPTF between two time points. The disclosure further provides methods to treat a subject with a cancer by administering a polynucleotide comprising an inhibitory BPTF nucleic acid and/or an agent that inhibits the expression or activity of BPTF.Type: ApplicationFiled: March 15, 2014Publication date: January 28, 2016Applicant: Sutter West Bay HospitalsInventors: Mohammed Kashani-Sabet, Altaf A. Dar
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Publication number: 20150320720Abstract: This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.Type: ApplicationFiled: July 17, 2015Publication date: November 12, 2015Applicant: Sutter West Bay HospitalsInventors: Sean D. McAllister, Pierre-Yves Desprez
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Patent number: 9084771Abstract: This disclosure provides compositions and method useful for treating cell proliferative disorders including cancer. The disclosure provides cannabidiol derivatives and compositions thereof either alone or in combination with THC or a derivative thereof.Type: GrantFiled: May 16, 2008Date of Patent: July 21, 2015Assignee: Sutter West Bay HospitalsInventors: Sean D. McAllister, Pierre-Yves Desprez
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Patent number: 8883200Abstract: Provided herein is a process for preparing a microparticulate complex of a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible organic solvent. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component, and a composition comprising water and the microparticulate complex. Further provided is a method of delivery of a nucleic acid-like component to a cell or to a patient by contacting the cell with or administering to the patient a composition comprising water and the microparticulate complex described herein. Still further, a charge-changing composition represented by the formula A-X—B is provided.Type: GrantFiled: July 11, 2013Date of Patent: November 11, 2014Assignee: Sutter West Bay HospitalsInventors: Keelung Hong, Wei Wen Zheng, Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes
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Patent number: 8779138Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.Type: GrantFiled: January 24, 2011Date of Patent: July 15, 2014Assignees: Sutter West Bay Hospital, Catholic Healthcare WestInventor: Li-Xi Yang
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Publication number: 20140161811Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).Type: ApplicationFiled: May 3, 2013Publication date: June 12, 2014Applicant: Sutter West Bay HospitalsInventors: Charles Cobbs, Liliana Soroceanu
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Patent number: 8716257Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.Type: GrantFiled: April 15, 2012Date of Patent: May 6, 2014Assignee: Sutter West Bay HospitalsInventors: Charles Cobbs, Liliana Soroceanu
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Publication number: 20140017300Abstract: Provided herein is a process for preparing a microparticulate complex of a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible organic solvent. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component, and a composition comprising water and the microparticulate complex. Further provided is a method of delivery of a nucleic acid-like component to a cell or to a patient by contacting the cell with or administering to the patient a composition comprising water and the microparticulate complex described herein. Still further, a charge-changing composition represented by the formula A-X—B is provided.Type: ApplicationFiled: July 11, 2013Publication date: January 16, 2014Applicant: Sutter West bay Hospital, DBA California Pacific Medical CenterInventors: Keelung Hong, Wei-Wen Zheng, Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes
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Patent number: 8563537Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.Type: GrantFiled: July 29, 2008Date of Patent: October 22, 2013Assignees: Sutter West Bay Hospital, Catholic Healthcare WestInventor: Li-Xi Yang
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Publication number: 20130209483Abstract: The disclosure relates to cannabinoid derivative compounds, pharmaceutical compositions made thereof, and methods for treating various diseases and disorders including cancer.Type: ApplicationFiled: November 30, 2012Publication date: August 15, 2013Applicant: SUTTER WEST BAY HOSPITALSInventor: SUTTER WEST BAY HOSPITALS
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Patent number: 8496961Abstract: A process for preparing a microparticulate complex is provided. The process comprises (a) combining a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible, organic solvent to form a mixture wherein the PFC and the NAC are independently molecularly or micellarly soluble in the aqueous/organic solvent system, and (b) reducing the amount of the organic solvent in the mixture. This effects formation of the microparticulate complex of the NAC and the PFC. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component forming an approximately spherical particle, wherein the particle-forming component encloses an interior of the particle containing the nucleic acid-like component and the so-enclosed interior volume has less than about 50% (preferably less than 20%) of the volume containing free water.Type: GrantFiled: May 15, 2003Date of Patent: July 30, 2013Assignee: Sutter West Bay HospitalInventors: Keelung Hong, Wei-Wen Zheng, Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes
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Patent number: 8435510Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).Type: GrantFiled: August 7, 2008Date of Patent: May 7, 2013Assignee: Sutter West Bay HospitalsInventors: Charles Cobbs, Liliana Soroceanu
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Publication number: 20120264675Abstract: The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV) and methods of treating diseases and disorders, including cell proliferative disorders, associated with CMV infection.Type: ApplicationFiled: April 15, 2012Publication date: October 18, 2012Applicant: SUTTER WEST BAY HOSPITALSInventors: Charles Cobbs, Liliana Soroceanu
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Patent number: 8158809Abstract: 4-O esters of podophyllotoxin and 4?-demethylepipodophyllotoxin are provided. The compounds are 4-O esters of an alkanoic acid or substituted alkanoic acid and podophyllotoxin and 4?-demethylepipodophyllotoxin. The compounds are useful for treating cancer.Type: GrantFiled: August 3, 2009Date of Patent: April 17, 2012Assignees: Sutter West Bay Hospitals, Catholic Healthcare WestInventor: Li-Xi Yang
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Publication number: 20120076795Abstract: The disclosure relates to the discovery that systemic administration of an antibody that binds to PECAM-1 increases body weight while suppressing the metastatic spread of a wide variety of different tumor types which are typically fatal in humans.Type: ApplicationFiled: September 27, 2011Publication date: March 29, 2012Applicant: Sutter West Bay Hospitals D/B/A California Pacific Medical CenterInventor: Robert DEBS
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Patent number: 7875602Abstract: Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.Type: GrantFiled: May 30, 2006Date of Patent: January 25, 2011Assignees: Sutter West Bay Hospitals, Catholic Healthcare WestInventor: Li-Xi Yang