Patents Assigned to Suzhou Qi Biodesign Biotechnology Company Limited
  • METHOD FOR IMPROVING EFFICIENCY OF GENETIC TRANSFORMATION AND GENE EDITING IN PLANTS
    Publication number: 20240167048
    Abstract: The invention belongs to the field of genetic engineering in plants. In particular, the invention relates to a method for improving efficiency of genetic transformation and gene editing in plants. More particularly, the invention relates to a method for improving regeneration efficiency of genetic transformation and/or gene editing efficiency in plants by expression of gene NiR which promotes nitrogen metabolism in plants.
    Type: Application
    Filed: March 24, 2022
    Publication date: May 23, 2024
    Applicant: Suzhou Qi Biodesign Biotechnology Company Limited
    Inventors: Caixia Gao, Lu Chen
  • MULTIPLEX GENOME EDITING METHOD AND SYSTEM
    Publication number: 20240117368
    Abstract: The invention relates to the field of plant genetic engineering. In particular, the invention relates to a method and system for multiplex genome editing suitable for plants, especially crops. More particularly, the invention relates to a CRISPR nickase-based system and method, which can simultaneously carry out different types of genome editing.
    Type: Application
    Filed: March 4, 2021
    Publication date: April 11, 2024
    Applicant: Suzhou Qi Biodesign Biotechnology Company Limited
    Inventors: Caixia Gao, Chao Li, Kunling Chen
  • GENOME EDITING METHOD
    Publication number: 20240011052
    Abstract: The present invention relates to the field of genetic engineering. In particular, the present invention relates to a genome editing method with high efficiency and high specificity. More specifically, the present invention relates to a method for increasing the efficiency of site-directed modification of a target sequence in a genome of an organism by a high-specificity Cas9 nuclease variant.
    Type: Application
    Filed: April 3, 2023
    Publication date: January 11, 2024
    Applicant: SUZHOU QI BIODESIGN BIOTECHNOLOGY COMPANY LIMITED
    Inventors: Caixia GAO, Huawei ZHANG, Dingbo ZHANG
  • IMPROVED CYTOSINE BASE EDITING SYSTEM
    Publication number: 20230313234
    Abstract: The present invention belongs to the field of gene editing. In particular, the present invention relates to an improved cytosine base editing system which has a significantly reduced genome-wide off target effect and a narrow editing window.
    Type: Application
    Filed: March 4, 2021
    Publication date: October 5, 2023
    Applicant: Suzhou Qi Biodesign biotechnology Company Limited
    Inventors: Caixia Gao, Yanpeng Wang, Shuai Jin, Yuan Zong
  • METHOD FOR DETECTING RANDOM OFF-TARGET EFFECT OF SINGLE-BASE EDITING SYSTEM
    Publication number: 20230295710
    Abstract: The present invention belongs to the field of gene editing, and particularly relates to a method and means for detecting genome wide random off-target effect of a base editing system in a rapid and high-throughput mode.
    Type: Application
    Filed: March 4, 2021
    Publication date: September 21, 2023
    Applicant: Suzhou Qi Biodesign Biotechnology Company Limited
    Inventors: Caixia Gao, Shuai Jin, Zixu Zhu, Hongyuan Fei