Patents Assigned to SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.
  • Bromodomain inhibitor compound and use thereof
    Patent number: 11427593
    Abstract: The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: August 30, 2022
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Suzhou Suplead Life Sciences Co., Ltd.
    Inventors: Bing Zhou, Cheng Luo, Zizhou Li, Yaxi Yang, Shijie Chen, Hong Ding, Hualiang Jiang, Gang Qiao, Xinjun Wang, Senhao Xiao
  • Triazolopyrimidine, triazolopyridine compounds, and the composition thereof for treating PRC2-mediated diseases
    Patent number: 11013745
    Abstract: The present invention provides a compound represented by formula I, pharmaceutically acceptable salts, enantiomers, diastereomers or racemates thereof, the preparation method thereof, the pharmaceutical composition comprising the same, and the use thereof in the preparation of a medicament for treating a disease or condition mediated by EED and/or PRC2. The compound of the present invention can be used treating PRC2-mediated diseases or conditions.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: May 25, 2021
    Assignees: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, SUZHOU SUPLEAD LIFE SCIENCES CO., LTD.
    Inventors: Bing Zhou, Cheng Luo, Yaxi Yang, Yuanyuan Zhang, Daohai Du, Hualiang Jiang, Gang Qiao, Xinjun Wang