Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
Type:
Grant
Filed:
July 13, 2014
Date of Patent:
May 30, 2017
Assignee:
SWITCHGEAR GENOMICS, INC.
Inventors:
Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
Type:
Application
Filed:
July 13, 2014
Publication date:
December 11, 2014
Applicant:
SWITCHGEAR GENOMICS, INC.
Inventors:
Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins
Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
Type:
Grant
Filed:
September 16, 2009
Date of Patent:
August 26, 2014
Assignee:
SwitchGear Genomics, Inc.
Inventors:
Shelley Force Aldred, Nathan D. Trinklein, Michael Rose, Patrick Collins