Abstract: This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
Type:
Application
Filed:
September 16, 2009
Publication date:
March 17, 2011
Applicant:
SwitchGear Genomics, Inc., a Delaware Corporation
Inventors:
Shelley Force Aldred, Michael Rose, Patrick Collins, Nathan D. Trinklein