Abstract: The invention is directed to compositions comprising, and methods of using, racemic N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (−)-N-desmethylzopiclone in the treatment and prevention of diseases and conditions in mammals. The invention is further directed to novel methods of preparing N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (−)-N-desmethylzopiclone.
Type:
Grant
Filed:
April 13, 2000
Date of Patent:
January 15, 2002
Assignee:
Swpracor, Inc.
Inventors:
Thomas P. Jerussi, Chrisantha H. Senanayake, Paul D. Rubin, Fran A. McConville