Abstract: A compound TSYI-ZAC (Zhankuic acid C) used in a method for treating dengue virus infection, in which a pharmaceutical composition can further comprise a 4,7-dimethoxy-5-methyl-1,3-benzodioxole compound capable of inhibiting dengue virus infection by down-regulating an expression of IL-6 and IL-8, and increasing a secretion of IFN-?.

Abstract: Present invention provides a bioactive fraction of Anisomeles indica, TSYI-813, and its preparation which includes extracting Anisomeles indica using an alcohol solvent, fractioning the extract of Anisomeles indica by an organic solvent and water, and purifying via a silica column chromatography with 10:1˜10:5 hexane/ethyl acetate for sequential elution to give the bioactive fraction of Anisomeles indica, TSYI-813. The bioactive fraction of Anisomeles indica, TSYI-813, disclosed in present invention can can be used as an effective ingredient for treating or improving gastric ulcers, including reducing the area of ulcer and inflammation in the stomach tissue.